biostudies-literature00610Herrmann ATNIGMS NIH HHS5962-3https://www.ebi.ac.uk/biostudies/studies/S-EPMC2861154biostudies-literatureUnknown132(17)A hydroxyl group-directed, highly regio- and stereoselective transposition of allylic alcohols based on rhenium catalysis has been developed. The method is suitable for a direct isomerization of acetals into the thermodynamically preferred isomer as long as one of the hydroxyl groups is allylic. This method will expand the scope of rhenium-catalyzed alcohol transpositions for complex molecule synthesis.Journal of the American Chemical SocietyRegio- and stereocontrol in rhenium-catalyzed transposition of allylic alcohols.PMC2861154R01 GM077379-02R01 GM077379Saito TZakarian AHerrmann ATStivala CETom J61falseRegio- and stereocontrol in rhenium-catalyzed transposition of allylic alcohols.A hydroxyl group-directed, highly regio- and stereoselective transposition of allylic alcohols based on rhenium catalysis has been developed. The method is suitable for a direct isomerization of acetals into the thermodynamically preferred isomer as long as one of the hydroxyl groups is allylic. This method will expand the scope of rhenium-catalyzed alcohol transpositions for complex molecule synthesis.2010-01-01T00:00:00Z2010 May2020-11-01T08:13:43Z2019-03-26T23:28:37ZS-EPMC28611542038781110.1021/ja101673v