{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Xie X"],"funding":["NIGMS NIH HHS"],"pagination":["3847-50"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC2882174"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["75(11)"],"pubmed_abstract":["Alkylidenecyclopropanes can be synthesized from enantiomerically enriched cyclopropene derivatives with >99% stereotransfer and good to excellent yield. The protocol comprises the stereoselective reaction of Grignard reagents with 1-alkoxymethyl-3-hydroxymethylcyclopropenes and a stereospecific [1,3] carbon shift reaction."],"journal":["The Journal of organic chemistry"],"pubmed_title":["Stereospecific synthesis of alkylidenecyclopropanes via sequential cyclopropene carbomagnesation/1,3-carbon shift."],"pmcid":["PMC2882174"],"funding_grant_id":["R01 GM068640-07","R01 GM068650","R01 GM068640"],"pubmed_authors":["Yang Z","Fox JM","Xie X"],"additional_accession":[]},"is_claimable":false,"name":"Stereospecific synthesis of alkylidenecyclopropanes via sequential cyclopropene carbomagnesation/1,3-carbon shift.","description":"Alkylidenecyclopropanes can be synthesized from enantiomerically enriched cyclopropene derivatives with >99% stereotransfer and good to excellent yield. The protocol comprises the stereoselective reaction of Grignard reagents with 1-alkoxymethyl-3-hydroxymethylcyclopropenes and a stereospecific [1,3] carbon shift reaction.","dates":{"release":"2010-01-01T00:00:00Z","publication":"2010 Jun","modification":"2025-05-18T13:38:14.751Z","creation":"2025-05-18T13:38:14.751Z"},"accession":"S-EPMC2882174","cross_references":{"pubmed":["20462206"],"doi":["10.1021/jo1002938"]}}