biostudies-literatureMcCleary NJNCRR NIH HHSNCI NIH HHS957-66https://www.ebi.ac.uk/biostudies/studies/S-EPMC2884300biostudies-literatureUnknown116(4)<h4>Background</h4>Cigarette smoking has been shown to increase the risk of developing colorectal cancer, particularly smoking early in life. Little is known about the impact of tobacco use on colon cancer recurrence among colon cancer survivors.<h4>Methods</h4>The authors prospectively collected lifetime smoking history from stage III colon cancer patients enrolled in a phase 3 trial via self-report questionnaires during and 6 months after completion of adjuvant chemotherapy. Smoking status was defined as never, current, or past. Lifetime pack-years were defined as number of lifetime packs of cigarettes. Patients were followed for recurrence or death.<h4>Results</h4>Data on smoking history were captured on 1045 patients with stage III colon cancer receiving adjuvant therapy (46% never smoCancerImpact of smoking on patients with stage III colon cancer: results from Cancer and Leukemia Group B 89803.PMC2884300R01 CA118553-03CA32101CA33601CA35415CA31946CA46282CA38926P50 CA127003-01U10 CA031946R01 CA118553CA17145CA77651U10 CA033601UL1 RR025741CA47559P50 CA127003CA32291Hollis DGoldberg RSchaefer PSaltz LBBenson AMcCleary NJNiedzwiecki DWhittom RMeyerhardt JAHantel AfalseImpact of smoking on patients with stage III colon cancer: results from Cancer and Leukemia Group B 89803.<h4>Background</h4>Cigarette smoking has been shown to increase the risk of developing colorectal cancer, particularly smoking early in life. Little is known about the impact of tobacco use on colon cancer recurrence among colon cancer survivors.<h4>Methods</h4>The authors prospectively collected lifetime smoking history from stage III colon cancer patients enrolled in a phase 3 trial via self-report questionnaires during and 6 months after completion of adjuvant chemotherapy. Smoking status was defined as never, current, or past. Lifetime pack-years were defined as number of lifetime packs of cigarettes. Patients were followed for recurrence or death.<h4>Results</h4>Data on smoking history were captured on 1045 patients with stage III colon cancer receiving adjuvant therapy (46% never smo2010-01-01T00:00:00Z2010 Feb2025-04-22T15:47:15.405Z2019-03-27T00:31:27ZS-EPMC28843002005272310.1002/cncr.24866