{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["5(8)"],"submitter":["Reveiz L"],"pubmed_abstract":["<h4>Background</h4>Although randomized clinical trials (RCTs) are considered the gold standard of evidence, their reporting is often suboptimal. Trial registries have the potential to contribute important methodologic information for critical appraisal of study results.<h4>Methods and findings</h4>The objective of the study was to evaluate the reporting of key methodologic study characteristics in trial registries. We identified a random sample (n = 265) of actively recruiting RCTs using the World Health Organization International Clinical Trials Registry Platform (ICTRP) search portal in 2008. We assessed the reporting of relevant domains from the Cochrane Collaboration's 'Risk of bias' tool and other key methodological aspects. Our primary outcomes were the proportion of registry records"],"journal":["PloS one"],"pagination":["e12484"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC2930852"],"repository":["biostudies-literature"],"pubmed_title":["Reporting of methodologic information on trial registries for quality assessment: a study of trial records retrieved from the WHO search portal."],"pmcid":["PMC2930852"],"pubmed_authors":["Granados CE","Bonfill X","Rada D","Cardona AF","Martinez M","Chan AW","Krleza-Jeric K","Pinart M","Etxeandia I","Reveiz L"],"additional_accession":[]},"is_claimable":false,"name":"Reporting of methodologic information on trial registries for quality assessment: a study of trial records retrieved from the WHO search portal.","description":"<h4>Background</h4>Although randomized clinical trials (RCTs) are considered the gold standard of evidence, their reporting is often suboptimal. Trial registries have the potential to contribute important methodologic information for critical appraisal of study results.<h4>Methods and findings</h4>The objective of the study was to evaluate the reporting of key methodologic study characteristics in trial registries. We identified a random sample (n = 265) of actively recruiting RCTs using the World Health Organization International Clinical Trials Registry Platform (ICTRP) search portal in 2008. We assessed the reporting of relevant domains from the Cochrane Collaboration's 'Risk of bias' tool and other key methodological aspects. Our primary outcomes were the proportion of registry records","dates":{"release":"2010-01-01T00:00:00Z","publication":"2010 Aug","modification":"2025-04-26T11:32:13.999Z","creation":"2019-03-26T23:08:55Z"},"accession":"S-EPMC2930852","cross_references":{"pubmed":["20824212"],"doi":["10.1371/journal.pone.0012484"]}}