biostudies-literatureUnknown65(Pt 7)Suwunwong TThe mol-ecule of the title heteroaryl chalcone, C(16)H(16)O(4)S, which consists of substituted thio-phene and benzene rings bridged by the prop-2-en-1-one group, is slightly twisted. The dihedral angle between the thio-phene and 3,4,5-trimethoxy-phenyl rings is 12.18 (4)°. The three meth-oxy groups have two different conformations; two meth-oxy groups are coplanar [C-O-C-C torsion angles = -1.38 (12) and 0.47 (12)°] whereas the third is (-)-synclinal with the benzene ring. In the crystal structure, adjacent mol-ecules are linked in a face-to-side manner into chains along the c axis by weak C-H⋯O(enone) inter-actions. These chains are stacked along the b axis by weak C-H⋯O(meth-oxy) inter-actions.Acta crystallographica. Section E, Structure reports onlineo1575-6https://www.ebi.ac.uk/biostudies/studies/S-EPMC2969210biostudies-literature(E)-1-(2-Thien-yl)-3-(3,4,5-trimethoxy-phen-yl)prop-2-en-1-one.PMC2969210Fun HKChantrapromma SPakdeevanich PSuwunwong Tfalse(E)-1-(2-Thien-yl)-3-(3,4,5-trimethoxy-phen-yl)prop-2-en-1-one.The mol-ecule of the title heteroaryl chalcone, C(16)H(16)O(4)S, which consists of substituted thio-phene and benzene rings bridged by the prop-2-en-1-one group, is slightly twisted. The dihedral angle between the thio-phene and 3,4,5-trimethoxy-phenyl rings is 12.18 (4)°. The three meth-oxy groups have two different conformations; two meth-oxy groups are coplanar [C-O-C-C torsion angles = -1.38 (12) and 0.47 (12)°] whereas the third is (-)-synclinal with the benzene ring. In the crystal structure, adjacent mol-ecules are linked in a face-to-side manner into chains along the c axis by weak C-H⋯O(enone) inter-actions. These chains are stacked along the b axis by weak C-H⋯O(meth-oxy) inter-actions.2009-01-01T00:00:00Z2009 Jun2025-04-04T21:05:11.743Z2019-03-27T00:00:09ZS-EPMC29692102158285310.1107/S1600536809021850