{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Kim JH"],"funding":["Intramural NIH HHS","NIGMS NIH HHS"],"pagination":["638-51"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC3034128"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["54(7)"],"pubmed_abstract":["<h4>Objectives</h4>We developed and tested a novel transcatheter circumferential annuloplasty technique to reduce mitral regurgitation in porcine ischemic cardiomyopathy.<h4>Background</h4>Catheter-based annuloplasty for secondary mitral regurgitation exploits the proximity of the coronary sinus to the mitral annulus, but is limited by anatomic variants and coronary artery entrapment.<h4>Methods</h4>The procedure, \"cerclage annuloplasty,\" is guided by magnetic resonance imaging (MRI) roadmaps fused with live X-ray. A coronary sinus guidewire traverses a short segment of the basal septal myocardium to re-enter the right heart where it is exchanged for a suture. Tension is applied interactively during imaging and secured with a locking device.<h4>Results</h4>We found 2 feasible suture pathwa"],"journal":["Journal of the American College of Cardiology"],"pubmed_title":["Mitral cerclage annuloplasty, a novel transcatheter treatment for secondary mitral valve regurgitation: initial results in swine."],"pmcid":["PMC3034128"],"funding_grant_id":["Z01 HL005062-05","T32 GM008169"],"pubmed_authors":["Sampath S","Ozturk C","Sonmez M","Wright VJ","Berry C","Schenke WH","Raman VK","Kim AH","Faranesh AZ","Kocaturk O","Lederman RJ","Saikus CE","McVeigh ER","Kim JH","Derbyshire JA"],"additional_accession":[]},"is_claimable":false,"name":"Mitral cerclage annuloplasty, a novel transcatheter treatment for secondary mitral valve regurgitation: initial results in swine.","description":"<h4>Objectives</h4>We developed and tested a novel transcatheter circumferential annuloplasty technique to reduce mitral regurgitation in porcine ischemic cardiomyopathy.<h4>Background</h4>Catheter-based annuloplasty for secondary mitral regurgitation exploits the proximity of the coronary sinus to the mitral annulus, but is limited by anatomic variants and coronary artery entrapment.<h4>Methods</h4>The procedure, \"cerclage annuloplasty,\" is guided by magnetic resonance imaging (MRI) roadmaps fused with live X-ray. A coronary sinus guidewire traverses a short segment of the basal septal myocardium to re-enter the right heart where it is exchanged for a suture. Tension is applied interactively during imaging and secured with a locking device.<h4>Results</h4>We found 2 feasible suture pathwa","dates":{"release":"2009-01-01T00:00:00Z","publication":"2009 Aug","modification":"2025-04-22T05:06:03.339Z","creation":"2019-03-27T00:38:43Z"},"accession":"S-EPMC3034128","cross_references":{"pubmed":["19660696"],"doi":["10.1016/j.jacc.2009.03.071"]}}