{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Ando S"],"funding":["NCI NIH HHS"],"pagination":["2556-66"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC3045475"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["133(8)"],"pubmed_abstract":["Mercury is a major threat to the environment and to human health. It is highly desirable to develop a user-friendly kit for on-site mercury detection. Such a method must be able to detect mercury below the threshold levels for drinking water, 1-2 ppb. We developed a fluorescence method based on the oxymercuration of vinyl ethers to detect mercury in dental and environmental samples. Chloride ions interfered with the oxymercuration reaction, but the addition of AgNO(3) solved this problem. Fine electronic and structural tuning led to the development of a more responsive probe that was less sensitive to chloride ion interference. This second-generation probe could detect 1 ppb mercury ions in water."],"journal":["Journal of the American Chemical Society"],"pubmed_title":["Development and applications of fluorogenic probes for mercury(II) based on vinyl ether oxymercuration."],"pmcid":["PMC3045475"],"funding_grant_id":["R01 CA120792","R01CA120792","R01 CA120792-04"],"pubmed_authors":["Koide K","Ando S"],"additional_accession":[]},"is_claimable":false,"name":"Development and applications of fluorogenic probes for mercury(II) based on vinyl ether oxymercuration.","description":"Mercury is a major threat to the environment and to human health. It is highly desirable to develop a user-friendly kit for on-site mercury detection. Such a method must be able to detect mercury below the threshold levels for drinking water, 1-2 ppb. We developed a fluorescence method based on the oxymercuration of vinyl ethers to detect mercury in dental and environmental samples. Chloride ions interfered with the oxymercuration reaction, but the addition of AgNO(3) solved this problem. Fine electronic and structural tuning led to the development of a more responsive probe that was less sensitive to chloride ion interference. This second-generation probe could detect 1 ppb mercury ions in water.","dates":{"release":"2011-01-01T00:00:00Z","publication":"2011 Mar","modification":"2024-10-15T20:39:05.1Z","creation":"2019-03-26T23:28:42Z"},"accession":"S-EPMC3045475","cross_references":{"pubmed":["21294513"],"doi":["10.1021/ja108028m"]}}