biostudies-literatureUnknown11Nilsson A<h4>Background</h4>Hexokinase catalyzes the phosphorylation of glucose and fructose, but it is also involved in sugar sensing in both fungi and plants. We have previously described two types of hexokinases in the moss Physcomitrella. Type A, exemplified by PpHxk1, the major hexokinase in Physcomitrella, is a soluble protein that localizes to the chloroplast stroma. Type B, exemplified by PpHxk2, has an N-terminal membrane anchor. Both types are found also in vascular plants, and localize to the chloroplast stroma and mitochondrial membranes, respectively.<h4>Results</h4>We have now characterized all 11 hexokinase encoding genes in Physcomitrella. Based on their N-terminal sequences and intracellular localizations, three of the encoded proteins are type A hexokinases and four are type B hexBMC plant biology32https://www.ebi.ac.uk/biostudies/studies/S-EPMC3045890biostudies-literatureTwo novel types of hexokinases in the moss Physcomitrella patens.PMC3045890Olsson TUlfstedt MThelander MRonne HNilsson AfalseTwo novel types of hexokinases in the moss Physcomitrella patens.<h4>Background</h4>Hexokinase catalyzes the phosphorylation of glucose and fructose, but it is also involved in sugar sensing in both fungi and plants. We have previously described two types of hexokinases in the moss Physcomitrella. Type A, exemplified by PpHxk1, the major hexokinase in Physcomitrella, is a soluble protein that localizes to the chloroplast stroma. Type B, exemplified by PpHxk2, has an N-terminal membrane anchor. Both types are found also in vascular plants, and localize to the chloroplast stroma and mitochondrial membranes, respectively.<h4>Results</h4>We have now characterized all 11 hexokinase encoding genes in Physcomitrella. Based on their N-terminal sequences and intracellular localizations, three of the encoded proteins are type A hexokinases and four are type B hex2011-01-01T00:00:00Z2011 Feb2025-04-04T21:03:55.949Z2019-03-27T00:39:15ZS-EPMC30458902132032510.1186/1471-2229-11-32