{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["108 Suppl 1"],"submitter":["Scott KP"],"pubmed_abstract":["Roseburia inulinivorans is a recently identified motile representative of the Firmicutes that contributes to butyrate formation from a variety of dietary polysaccharide substrates in the human large intestine. Microarray analysis was used here to investigate substrate-driven gene-expression changes in R. inulinivorans A2-194. A cluster of fructo-oligosaccharide/inulin utilization genes induced during growth on inulin included one encoding a β-fructofuranosidase protein that was prominent in the proteome of inulin-grown cells. This cluster also included a 6-phosphofructokinase and an ABC transport system, whereas a distinct inulin-induced 1-phosphofructokinase was linked to a fructose-specific phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS II transport enzyme). Real-time"],"journal":["Proceedings of the National Academy of Sciences of the United States of America"],"pagination":["4672-9"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC3063597"],"repository":["biostudies-literature"],"pubmed_title":["Substrate-driven gene expression in Roseburia inulinivorans: importance of inducible enzymes in the utilization of inulin and starch."],"pmcid":["PMC3063597"],"pubmed_authors":["Young P","Martin JC","Potrykus J","Rucklidge G","Campbell G","Chassard C","Ramsay AG","Scott KP","Flint HJ","Mayer CD","Clerget M"],"additional_accession":[]},"is_claimable":false,"name":"Substrate-driven gene expression in Roseburia inulinivorans: importance of inducible enzymes in the utilization of inulin and starch.","description":"Roseburia inulinivorans is a recently identified motile representative of the Firmicutes that contributes to butyrate formation from a variety of dietary polysaccharide substrates in the human large intestine. Microarray analysis was used here to investigate substrate-driven gene-expression changes in R. inulinivorans A2-194. A cluster of fructo-oligosaccharide/inulin utilization genes induced during growth on inulin included one encoding a β-fructofuranosidase protein that was prominent in the proteome of inulin-grown cells. This cluster also included a 6-phosphofructokinase and an ABC transport system, whereas a distinct inulin-induced 1-phosphofructokinase was linked to a fructose-specific phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS II transport enzyme). Real-time","dates":{"release":"2011-01-01T00:00:00Z","publication":"2011 Mar","modification":"2026-04-29T08:07:44.457Z","creation":"2019-03-27T00:40:00Z"},"accession":"S-EPMC3063597","cross_references":{"pubmed":["20679207"],"doi":["10.1073/pnas.1000091107"]}}