{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Rizzi TS"],"funding":["NIDA NIH HHS","NIMH NIH HHS","Medical Research Council","Dutch Research Council (NWO)","NINDS NIH HHS","Wellcome Trust","Biotechnology and Biological Sciences Research Council"],"pagination":["145-57"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC3085124"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["156(2)"],"pubmed_abstract":["Intelligence is a highly heritable trait for which it has proven difficult to identify the actual genes. In the past decade, five whole-genome linkage scans have suggested genomic regions important to human intelligence; however, so far none of the responsible genes or variants in those regions have been identified. Apart from these regions, a handful of candidate genes have been identified, although most of these are in need of replication. The recent growth in publicly available data sets that contain both whole genome association data and a wealth of phenotypic data, serves as an excellent resource for fine mapping and candidate gene replication. We used the publicly available data of 947 families participating in the International Multi-Centre ADHD Genetics (IMAGE) study to conduct an "],"journal":["American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics"],"pubmed_title":["The ATXN1 and TRIM31 genes are related to intelligence in an ADHD background: evidence from a large collaborative study totaling 4,963 subjects."],"pmcid":["PMC3085124"],"funding_grant_id":["NS049067","BB/F019394/1","K24 DA023464","G0800582","R01 MH062873","G9817803B","076467/Z05/z","R01MH62873","R01 NS049067","R01MH081803","R01 MH081803","480-05-003","G0600705","G0700704","G03001896"],"pubmed_authors":["Anney R","Ashley-Koch AE","Steinhausen HC","Arias-Vasquez A","Martin NG","Tenesa A","Rizzi TS","Franke B","Van der Sluis S","Faraone SV","Evans DM","Gill M","Rothenberger A","Buitelaar J","Timpson NJ","Harris SE","Deary IJ","Oades RD","Taylor E","Anastopoulos AD","Ebstein R","Asherson P","Wright MJ","Banaschewski T","Montgomery GW","Garrett ME","Markunas CA","Sergeant J","Porteous DJ","Kuntsi J","Posthuma D","Ruano D","Kollins SH","Davey Smith G","Hansell NK","Starr JM","St Pourcain B","Davies G","Mulas F","Miranda A","Rommelse N","Sonuga-Barke E","Roeyers H"],"additional_accession":[]},"is_claimable":false,"name":"The ATXN1 and TRIM31 genes are related to intelligence in an ADHD background: evidence from a large collaborative study totaling 4,963 subjects.","description":"Intelligence is a highly heritable trait for which it has proven difficult to identify the actual genes. In the past decade, five whole-genome linkage scans have suggested genomic regions important to human intelligence; however, so far none of the responsible genes or variants in those regions have been identified. Apart from these regions, a handful of candidate genes have been identified, although most of these are in need of replication. The recent growth in publicly available data sets that contain both whole genome association data and a wealth of phenotypic data, serves as an excellent resource for fine mapping and candidate gene replication. We used the publicly available data of 947 families participating in the International Multi-Centre ADHD Genetics (IMAGE) study to conduct an ","dates":{"release":"2011-01-01T00:00:00Z","publication":"2011 Mar","modification":"2026-05-01T08:27:54.775Z","creation":"2026-04-07T16:46:50.376Z"},"accession":"S-EPMC3085124","cross_references":{"pubmed":["21302343"],"doi":["10.1002/ajmg.b.31149"]}}