{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["10"],"submitter":["Sinha R"],"pubmed_abstract":["<h4>Background</h4>Alternative splicing (AS) involving tandem acceptors that are separated by three nucleotides (NAGNAG) is an evolutionarily widespread class of AS, which is well studied in Homo sapiens (human) and Mus musculus (mouse). It has also been shown to be common in the model seed plants Arabidopsis thaliana and Oryza sativa (rice). In one of the first studies involving sequence-based prediction of AS in plants, we performed a genome-wide identification and characterization of NAGNAG AS in the model plant Physcomitrella patens, a moss.<h4>Results</h4>Using Sanger data, we found 295 alternatively used NAGNAG acceptors in P. patens. Using 31 features and training and test datasets of constitutive and alternative NAGNAGs, we trained a classifier to predict the splicing outcome at NA"],"journal":["BMC plant biology"],"pagination":["76"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC3095350"],"repository":["biostudies-literature"],"pubmed_title":["Identification and characterization of NAGNAG alternative splicing in the moss Physcomitrella patens."],"pmcid":["PMC3095350"],"pubmed_authors":["Zimmer AD","Platzer M","Sinha R","Bolte K","Lang D","Rensing SA","Backofen R","Reski R"],"additional_accession":[]},"is_claimable":false,"name":"Identification and characterization of NAGNAG alternative splicing in the moss Physcomitrella patens.","description":"<h4>Background</h4>Alternative splicing (AS) involving tandem acceptors that are separated by three nucleotides (NAGNAG) is an evolutionarily widespread class of AS, which is well studied in Homo sapiens (human) and Mus musculus (mouse). It has also been shown to be common in the model seed plants Arabidopsis thaliana and Oryza sativa (rice). In one of the first studies involving sequence-based prediction of AS in plants, we performed a genome-wide identification and characterization of NAGNAG AS in the model plant Physcomitrella patens, a moss.<h4>Results</h4>Using Sanger data, we found 295 alternatively used NAGNAG acceptors in P. patens. Using 31 features and training and test datasets of constitutive and alternative NAGNAGs, we trained a classifier to predict the splicing outcome at NA","dates":{"release":"2010-01-01T00:00:00Z","publication":"2010 Apr","modification":"2026-05-04T00:03:19.043Z","creation":"2026-04-07T19:51:43.934Z"},"accession":"S-EPMC3095350","cross_references":{"pubmed":["20426810"],"doi":["10.1186/1471-2229-10-76"]}}