{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["67(Pt 4)"],"submitter":["Wang ZG"],"pubmed_abstract":["The title compound, C(20)H(22)Br(2)N(2)O(2)·0.25CH(4)O, was synthesized by the condensation reaction of salicyl-aldehyde with 4-(2-amino-3,5-dibromo-benzyl-amino)-cyclo-hexa-nol in methanol. There are four independent main mol-ecules and two half-occupied methanol solvent mol-ecules in the asymmetric unit. The dihedral angles between the two benzene rings in the four mol-ecules are 87.8 (6), 86.6 (6), 89.3 (6) and 83.1 (6)°. Each mol-ecule features an intra-molecular O-H⋯N hydrogen bond and a short N-H⋯Br link. In the crystal components are linked by O-H⋯O hydrogen bonds."],"journal":["Acta crystallographica. Section E, Structure reports online"],"pagination":["o808-9"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC3099869"],"repository":["biostudies-literature"],"pubmed_title":["2-[6,8-Dibromo-3-(4-hy-droxy-cyclo-hex-yl)-1,2,3,4-tetra-hydro-quinazolin-2-yl]phenol methanol 0.25-solvate."],"pmcid":["PMC3099869"],"pubmed_authors":["Zhi F","Wang R","Wang ZG","Wang ML"],"additional_accession":[]},"is_claimable":false,"name":"2-[6,8-Dibromo-3-(4-hy-droxy-cyclo-hex-yl)-1,2,3,4-tetra-hydro-quinazolin-2-yl]phenol methanol 0.25-solvate.","description":"The title compound, C(20)H(22)Br(2)N(2)O(2)·0.25CH(4)O, was synthesized by the condensation reaction of salicyl-aldehyde with 4-(2-amino-3,5-dibromo-benzyl-amino)-cyclo-hexa-nol in methanol. There are four independent main mol-ecules and two half-occupied methanol solvent mol-ecules in the asymmetric unit. The dihedral angles between the two benzene rings in the four mol-ecules are 87.8 (6), 86.6 (6), 89.3 (6) and 83.1 (6)°. Each mol-ecule features an intra-molecular O-H⋯N hydrogen bond and a short N-H⋯Br link. In the crystal components are linked by O-H⋯O hydrogen bonds.","dates":{"release":"2011-01-01T00:00:00Z","publication":"2011 Apr","modification":"2025-04-04T23:26:55.038Z","creation":"2019-03-27T00:01:04Z"},"accession":"S-EPMC3099869","cross_references":{"pubmed":["21754095"],"doi":["10.1107/S1600536811007987"]}}