biostudies-literatureUnknown67(Pt 4)Wang ZGThe title compound, C(20)H(22)Br(2)N(2)O(2)·0.25CH(4)O, was synthesized by the condensation reaction of salicyl-aldehyde with 4-(2-amino-3,5-dibromo-benzyl-amino)-cyclo-hexa-nol in methanol. There are four independent main mol-ecules and two half-occupied methanol solvent mol-ecules in the asymmetric unit. The dihedral angles between the two benzene rings in the four mol-ecules are 87.8 (6), 86.6 (6), 89.3 (6) and 83.1 (6)°. Each mol-ecule features an intra-molecular O-H⋯N hydrogen bond and a short N-H⋯Br link. In the crystal components are linked by O-H⋯O hydrogen bonds.Acta crystallographica. Section E, Structure reports onlineo808-9https://www.ebi.ac.uk/biostudies/studies/S-EPMC3099869biostudies-literature2-[6,8-Dibromo-3-(4-hy-droxy-cyclo-hex-yl)-1,2,3,4-tetra-hydro-quinazolin-2-yl]phenol methanol 0.25-solvate.PMC3099869Zhi FWang RWang ZGWang MLfalse2-[6,8-Dibromo-3-(4-hy-droxy-cyclo-hex-yl)-1,2,3,4-tetra-hydro-quinazolin-2-yl]phenol methanol 0.25-solvate.The title compound, C(20)H(22)Br(2)N(2)O(2)·0.25CH(4)O, was synthesized by the condensation reaction of salicyl-aldehyde with 4-(2-amino-3,5-dibromo-benzyl-amino)-cyclo-hexa-nol in methanol. There are four independent main mol-ecules and two half-occupied methanol solvent mol-ecules in the asymmetric unit. The dihedral angles between the two benzene rings in the four mol-ecules are 87.8 (6), 86.6 (6), 89.3 (6) and 83.1 (6)°. Each mol-ecule features an intra-molecular O-H⋯N hydrogen bond and a short N-H⋯Br link. In the crystal components are linked by O-H⋯O hydrogen bonds.2011-01-01T00:00:00Z2011 Apr2025-04-04T23:26:55.038Z2019-03-27T00:01:04ZS-EPMC30998692175409510.1107/S1600536811007987