biostudies-literatureBodner MAustrian Science Fund FWF138-41https://www.ebi.ac.uk/biostudies/studies/S-EPMC3135241biostudies-literatureUnknown5(2)Reliable data are crucial for all research fields applying mitochondrial DNA (mtDNA) as a genetic marker. Quality control measures have been introduced to ensure the highest standards in sequence data generation, validation and a posteriori inspection. A phylogenetic alignment strategy has been widely accepted as a prerequisite for data comparability and database searches, for forensic applications, for reconstructions of human migrations and for correct interpretation of mtDNA mutations in medical genetics. There is continuing effort to enhance the number of worldwide population samples in order to contribute to a better understanding of human mtDNA variation. This has often lead to the analysis of convenience samples collected for other purposes, which might not meet the quality requiremForensic science international. GeneticsInspecting close maternal relatedness: Towards better mtDNA population samples in forensic databases.PMC3135241L 397Bodner MIrwin JAParson WCoble MDfalseInspecting close maternal relatedness: Towards better mtDNA population samples in forensic databases.Reliable data are crucial for all research fields applying mitochondrial DNA (mtDNA) as a genetic marker. Quality control measures have been introduced to ensure the highest standards in sequence data generation, validation and a posteriori inspection. A phylogenetic alignment strategy has been widely accepted as a prerequisite for data comparability and database searches, for forensic applications, for reconstructions of human migrations and for correct interpretation of mtDNA mutations in medical genetics. There is continuing effort to enhance the number of worldwide population samples in order to contribute to a better understanding of human mtDNA variation. This has often lead to the analysis of convenience samples collected for other purposes, which might not meet the quality requirem2011-01-01T00:00:00Z2011 Mar2025-04-27T02:23:47.617Z2019-03-27T03:07:01ZS-EPMC31352412106798610.1016/j.fsigen.2010.10.001