{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Schober M"],"funding":["Austrian Science Fund FWF"],"pagination":["4296-9"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC3155277"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["13(16)"],"pubmed_abstract":["A metallo-β-lactamase-type alkylsulfatase was found to catalyze the enantioselective hydrolysis of sec-alkylsulfates with strict inversion of configuration. This catalytic event, which does not have an analog in chemocatalysis, yields homochiral (S)-configurated alcohols and nonreacted sulfate esters. The latter could be converted into (S)-sec-alcohols as the sole product in up to >99% ee via a chemoenzymatic deracemization protocol on a preparative scale."],"journal":["Organic letters"],"pubmed_title":["A stereoselective inverting sec-alkylsulfatase for the deracemization of sec-alcohols."],"pmcid":["PMC3155277"],"funding_grant_id":["W 901"],"pubmed_authors":["Wagner U","Faber K","Macheroux P","Knaus T","Gully C","Gadler P","Kayer H","Birner-Grunberger R","Schober M"],"additional_accession":[]},"is_claimable":false,"name":"A stereoselective inverting sec-alkylsulfatase for the deracemization of sec-alcohols.","description":"A metallo-β-lactamase-type alkylsulfatase was found to catalyze the enantioselective hydrolysis of sec-alkylsulfates with strict inversion of configuration. This catalytic event, which does not have an analog in chemocatalysis, yields homochiral (S)-configurated alcohols and nonreacted sulfate esters. The latter could be converted into (S)-sec-alcohols as the sole product in up to >99% ee via a chemoenzymatic deracemization protocol on a preparative scale.","dates":{"release":"2011-01-01T00:00:00Z","publication":"2011 Aug","modification":"2026-05-05T03:56:25.829Z","creation":"2025-05-29T20:30:22.155Z"},"accession":"S-EPMC3155277","cross_references":{"pubmed":["21770430"],"doi":["10.1021/ol201635y"]}}