biostudies-literatureUnknown6(11)Yildiz Zeyrek FPlasmodium vivax infection has been gaining attention because of its re-emergence in several parts of the world. Southeastern Turkey is one of the places in which persistent focal malaria caused exclusively by P. vivax parasites occurs. Although control and elimination studies have been underway for many years, no detailed study has been conducted to understand the mechanisms underlying the ineffective control of malaria in this region. Here, for the first time, using serologic markers we try to extract as much information as possible in this region to get a glimpse of P. vivax transmission. We conducted a sero-immunological study, evaluating antibody responses of individuals living in Sanliurfa to four different P. vivax antigens; three blood-stage antigens (PvMSP1₁₉, PvAMA1-ecto, and PvSPloS onee28126https://www.ebi.ac.uk/biostudies/studies/S-EPMC3226671biostudies-literatureSerologic markers in relation to parasite exposure history help to estimate transmission dynamics of Plasmodium vivax.PMC3226671Yildiz Zeyrek FPalacpac NYuksel FYagi MArisue NIshii KJTsuboi TTanabe KCoban CHonjo KHorii TFujita YTakeo SfalseSerologic markers in relation to parasite exposure history help to estimate transmission dynamics of Plasmodium vivax.Plasmodium vivax infection has been gaining attention because of its re-emergence in several parts of the world. Southeastern Turkey is one of the places in which persistent focal malaria caused exclusively by P. vivax parasites occurs. Although control and elimination studies have been underway for many years, no detailed study has been conducted to understand the mechanisms underlying the ineffective control of malaria in this region. Here, for the first time, using serologic markers we try to extract as much information as possible in this region to get a glimpse of P. vivax transmission. We conducted a sero-immunological study, evaluating antibody responses of individuals living in Sanliurfa to four different P. vivax antigens; three blood-stage antigens (PvMSP1₁₉, PvAMA1-ecto, and PvS2011-01-01T00:00:00Z20112025-04-26T16:53:55.981Z2019-03-26T23:08:10ZS-EPMC32266712214052110.1371/journal.pone.0028126