{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Novikov Y"],"funding":["NIGMS NIH HHS"],"pagination":["1913-1915"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC3245685"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["52(16)"],"pubmed_abstract":["4-Phospho-D-erythronate is an intermediate in synthesis of pyridoxal 5'-phosphate in some bacteria and an inhibitor of ribose 5-phosphate isomerase. Previous synthetic schemes for the preparation of 4-phospho-D-erythronate required expensive precursors and typically gave low yields. We report a straightforward synthesis of 4-phospho-D-erythronate from the inexpensive precursor D-erythronolactone in 5 steps with a preparatively useful yield of 22%."],"journal":["Tetrahedron letters"],"pubmed_title":["A Simple Route for Synthesis of 4-Phospho-D-Erythronate."],"pmcid":["PMC3245685"],"funding_grant_id":["R01 GM083285-03","R01 GM083285"],"pubmed_authors":["Copley SD","Eaton BE","Novikov Y"],"additional_accession":[]},"is_claimable":false,"name":"A Simple Route for Synthesis of 4-Phospho-D-Erythronate.","description":"4-Phospho-D-erythronate is an intermediate in synthesis of pyridoxal 5'-phosphate in some bacteria and an inhibitor of ribose 5-phosphate isomerase. Previous synthetic schemes for the preparation of 4-phospho-D-erythronate required expensive precursors and typically gave low yields. We report a straightforward synthesis of 4-phospho-D-erythronate from the inexpensive precursor D-erythronolactone in 5 steps with a preparatively useful yield of 22%.","dates":{"release":"2011-01-01T00:00:00Z","publication":"2011 Apr","modification":"2025-04-22T04:48:31.75Z","creation":"2019-03-27T00:47:20Z"},"accession":"S-EPMC3245685","cross_references":{"pubmed":["22200980"],"doi":["10.1016/j.tetlet.2011.02.045"]}}