biostudies-literatureUnknown95(2)Lacroix E<h4>Background</h4>Whereas the negative effect of consuming trans fatty acids found in partially hydrogenated vegetable oils on cardiovascular disease (CVD) risk is well established, the effect of trans fatty acids from ruminant sources (rTFAs) on CVD risk factors has not yet been established, particularly among women.<h4>Objective</h4>We investigated the effects of a butter naturally enriched in rTFAs, of which vaccenic acid is the predominant isomer, on plasma lipid concentrations among healthy women.<h4>Design</h4>In a double-blind, randomized, crossover controlled study, 61 healthy women aged 19-70 y were fed 2 isoenergetic diets lasting 4 wk each. The 2 diets were defined as moderately high in rTFAs (3.7 g/d, 1.5% of daily energy) and control (0.9 g/d, 0.3% of daily energy).<h4>ResultThe American journal of clinical nutrition318-25https://www.ebi.ac.uk/biostudies/studies/S-EPMC3260067biostudies-literatureRandomized controlled study of the effect of a butter naturally enriched in trans fatty acids on blood lipids in healthy women.PMC3260067Couture PCyr ABaril-Gravel LLebeuf YPaquin PCharest ALacroix ELamarche BChouinard PYfalseRandomized controlled study of the effect of a butter naturally enriched in trans fatty acids on blood lipids in healthy women.<h4>Background</h4>Whereas the negative effect of consuming trans fatty acids found in partially hydrogenated vegetable oils on cardiovascular disease (CVD) risk is well established, the effect of trans fatty acids from ruminant sources (rTFAs) on CVD risk factors has not yet been established, particularly among women.<h4>Objective</h4>We investigated the effects of a butter naturally enriched in rTFAs, of which vaccenic acid is the predominant isomer, on plasma lipid concentrations among healthy women.<h4>Design</h4>In a double-blind, randomized, crossover controlled study, 61 healthy women aged 19-70 y were fed 2 isoenergetic diets lasting 4 wk each. The 2 diets were defined as moderately high in rTFAs (3.7 g/d, 1.5% of daily energy) and control (0.9 g/d, 0.3% of daily energy).<h4>Result2012-01-01T00:00:00Z2012 Feb2026-04-30T04:20:14.635Z2019-03-27T00:48:04ZS-EPMC32600672220531910.3945/ajcn.111.023408