{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["50(2)"],"submitter":["Yebra G"],"pubmed_abstract":["HIV-1 group M is classified into 9 subtypes, as well as recombinants favored by coinfection and superinfection events with different variants. Although HIV-1 subtype B is predominant in Europe, intersubtype recombinants are increasing in prevalence and complexity. In this study, phylogenetic analyses of pol sequences were performed to detect the HIV-1 circulating and unique recombinant forms (CRFs and URFs, respectively) in a Spanish cohort of antiretroviral treatment-naïve HIV-infected patients included in the Research Network on HIV/AIDS (CoRIS). Bootscanning and other methods were used to define complex recombinants not assigned to any subtype or CRF. A total of 670 available HIV-1 pol sequences from different patients were collected, of which 588 (87.8%) were assigned to HIV-1 subtype "],"journal":["Journal of clinical microbiology"],"pagination":["407-13"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC3264155"],"repository":["biostudies-literature"],"pubmed_title":["Most HIV type 1 non-B infections in the Spanish cohort of antiretroviral treatment-naive HIV-infected patients (CoRIS) are due to recombinant viruses."],"pmcid":["PMC3264155"],"pubmed_authors":["Gadea Pastor C","Montes Ramirez ML","Azkune Galparsoro H","Dronda F","Ligero C","Castro JM","de los Santos I","Antela A","Aguilar A","Castiello J","Arraiza MJ","Cervantes M","Pascual Pareja JF","Arrizabalaga J","Gutierrez C","Gutierrez F","Portilla Tamarit I","Sanz Sanz J","Sola Boneta J","Asensi V","Viciana P","Segura F","Veloso S","Blanes Julia M","Ramirez Schacke M","Riera M","Viciana I","Munoz Perez A","Peraire J","Sanjuan M","Rubio R","Giner Oncina L","Prieto A","Aleman Valls MR","Perez Valero I","Moreno A","Masia M","Muga R","Montolio F","Boix Martinez V","Salavert M","Lopez D","Munoz-Fernandez MA","Arribas Lopez JR","Viciana Ramos I","Cohort of the Spanish AIDS Research Network (CoRIS)","Losada E","Cuellar S","Manzardo C","Robledano Garcia C","Pinilla Moraza J","Murillas J","Aparicio AS","Ramos JM","Moreno S","Trastoy M","Camino X","Garcia Torre A","Perez-Martinez L","Jordano Montanez Q","Angeles Munoz M","Blanco JL","Gonzalez Garcia J","Pulido F","Gomez Sirvent JL","Perez-Cachafeiro S","Fiorante S","Ruiz L","Sobrino Vegas P","Aramburu MJ","del Valle J","Aleman MR","Iribarren JA","Hernandez B","Gomez-Mateos J","Palacios Munoz R","Garcia M","Sirvent JJ","Parra Ruiz J","del Amo J","Reus Banuls S","Castanares C","Garcia P","Dalmau D","Garcia F","Pumares M","Cano Sanchez A","Martinez E","Velli P","Gomez Rico C","Lopez Lirola AM","Metola L","Recio Sanchez E","Mora Rillo M","Lopez-Dupla M","Padilla S","Leyes M","Lacruz Rodrigo J","Matarranz M","Lopez Aldeguer J","Navarro G","Lopez-Cortes LF","Blanco F","Munoz Medina L","Gallego de la Fuente J","Perez I","Carton JA","Montero M","Ibanez L","Uriz J","Valle E","Hernandez Quero J","Navarro A","Peral Y","Marti P","Garcia-Alcaide F","Reparaz J","Alvarez D","Marquez Solero M","Qaneta RA","Penaranda M","Gutierrez Cuellar I","Rivas P","Miranda C","Sala M","Blanco JR","Arribas B","Caro-Murillo AM","Amengual MJ","Lozano de Leon F","Garcia-Merino I","Martin L","Garcia Garcia F","Cosin Ochaita J","Carrio Montiel JC","Hernandez Hernandez MI","Font R","Puerta Lopez T","Labarga P","Llenas J","Villalonga C","Macias J","Miro JM","Rodriguez Martin C","Vidal F","Clotet B","von Wichmann MA","Pineda V","Holguin A","de Diego M","Mozas D","Oteo JA","Sanz M","Berenguer J","Jaen Manzanera A","de Mulder M","Rodriguez-Arrondo F","Alonso Socas Mdel M","Tural C","Vargas M","Alejos Ferreras B","Bernardino de la Serna I","Arcaina Toledo P","Barreiro P","Tor J","Angels Ribas M","Padilla Ortega B","Bernal Morell E","Ruiz A","Diaz-Flores F","Sarria Cepeda C","Xercavins Valls M","Olona M","Zamora Vargas FJ","Ibarra V","Irigoyen Puig D","Pineda JA","Perez Elias MJ","Vilades C","Pascual Tome L","Miralles P","Soriano A","Rodriguez Fortunez P","Martinez-Lacasa J","Sanvisens A","Yebra G","Hernando Sebastian V","Pena Monje A","Lopez Bernaldo de Quiros JC","del Romero Guerrero J","Cairo Llobell M","Mallolas J","Gatell JM","Bustinduy MJ","Rodriguez J","Rodriguez C","Casado JL","Pena Sanchez de Rivera JM","Campins A","Soriano V","Santos Gonzalez J","Lopez-Dieguez M","Rodriguez V","Leal M","Penelo E","Mata R","Goenaga MA","Merino de Lucas E","Zamora L","Sanchez Conde M","Calabuig E","Irigoyen C","Portilla Sogorb J"],"additional_accession":[]},"is_claimable":false,"name":"Most HIV type 1 non-B infections in the Spanish cohort of antiretroviral treatment-naive HIV-infected patients (CoRIS) are due to recombinant viruses.","description":"HIV-1 group M is classified into 9 subtypes, as well as recombinants favored by coinfection and superinfection events with different variants. Although HIV-1 subtype B is predominant in Europe, intersubtype recombinants are increasing in prevalence and complexity. In this study, phylogenetic analyses of pol sequences were performed to detect the HIV-1 circulating and unique recombinant forms (CRFs and URFs, respectively) in a Spanish cohort of antiretroviral treatment-naïve HIV-infected patients included in the Research Network on HIV/AIDS (CoRIS). Bootscanning and other methods were used to define complex recombinants not assigned to any subtype or CRF. A total of 670 available HIV-1 pol sequences from different patients were collected, of which 588 (87.8%) were assigned to HIV-1 subtype ","dates":{"release":"2012-01-01T00:00:00Z","publication":"2012 Feb","modification":"2025-05-29T22:26:37.541Z","creation":"2025-05-29T22:26:37.541Z"},"accession":"S-EPMC3264155","cross_references":{"pubmed":["22162552"],"doi":["10.1128/JCM.05798-11","10.1128/jcm.05798-11"]}}