{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Boyd JS"],"funding":["NIGMS NIH HHS"],"pagination":["489-98"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC3276157"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["1(6)"],"pubmed_abstract":["The photosensory eyespot of the green alga Chlamydomonas reinhardtii is a model system for the study of organelle biogenesis and placement. Eyespot assembly and positioning are governed by several genetic loci that have been identified in forward genetic screens for phototaxis-defective mutants. These include the previously described miniature-eyespot mutant min1, the multiple-eyespot mutant mlt1, the eyeless mutants eye2 and eye3, and two previously uncharacterized eyespot mutants, min2 and mlt2. In this study, effects of miniature- and multiple-eyespot mutations and their combinations on the localization and expression levels of the rhodopsin photoreceptor channelrhodopsin-1 (ChR1) and the localization of the eyespot-assembly proteins EYE2 and EYE3 were examined. min2 mutants assemble a "],"journal":["G3 (Bethesda, Md.)"],"pubmed_title":["Miniature- and Multiple-Eyespot Loci in Chlamydomonas reinhardtii Define New Modulators of Eyespot Photoreception and Assembly."],"pmcid":["PMC3276157"],"funding_grant_id":["T32 GM008659"],"pubmed_authors":["Dieckmann CL","Lamb MR","Boyd JS"],"additional_accession":[]},"is_claimable":false,"name":"Miniature- and Multiple-Eyespot Loci in Chlamydomonas reinhardtii Define New Modulators of Eyespot Photoreception and Assembly.","description":"The photosensory eyespot of the green alga Chlamydomonas reinhardtii is a model system for the study of organelle biogenesis and placement. Eyespot assembly and positioning are governed by several genetic loci that have been identified in forward genetic screens for phototaxis-defective mutants. These include the previously described miniature-eyespot mutant min1, the multiple-eyespot mutant mlt1, the eyeless mutants eye2 and eye3, and two previously uncharacterized eyespot mutants, min2 and mlt2. In this study, effects of miniature- and multiple-eyespot mutations and their combinations on the localization and expression levels of the rhodopsin photoreceptor channelrhodopsin-1 (ChR1) and the localization of the eyespot-assembly proteins EYE2 and EYE3 were examined. min2 mutants assemble a ","dates":{"release":"2011-01-01T00:00:00Z","publication":"2011 Nov","modification":"2025-04-26T07:43:15.77Z","creation":"2019-03-27T00:48:56Z"},"accession":"S-EPMC3276157","cross_references":{"pubmed":["22384359"],"doi":["10.1534/g3.111.000679"]}}