{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["190(4)"],"submitter":["Henikoff S"],"funding":["Howard Hughes Medical Institute"],"pubmed_abstract":["The \"point\" centromere of budding yeast is genetically defined by an ≈ 125-bp sequence. Recent fluorescence measurements of kinetochore clusters have suggested that this sequence specifies multiple centromere histone 3 (CenH3) nucleosomes. However, high-resolution mapping demonstrates that there is only one CenH3 nucleosome per centromere, providing biochemical confirmation of the point centromere model."],"journal":["Genetics"],"pagination":["1575-7"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC3316665"],"repository":["biostudies-literature"],"pubmed_title":["\"Point\" centromeres of Saccharomyces harbor single centromere-specific nucleosomes."],"pmcid":["PMC3316665"],"pubmed_authors":["Henikoff S","Henikoff JG"],"additional_accession":[]},"is_claimable":false,"name":"\"Point\" centromeres of Saccharomyces harbor single centromere-specific nucleosomes.","description":"The \"point\" centromere of budding yeast is genetically defined by an ≈ 125-bp sequence. Recent fluorescence measurements of kinetochore clusters have suggested that this sequence specifies multiple centromere histone 3 (CenH3) nucleosomes. However, high-resolution mapping demonstrates that there is only one CenH3 nucleosome per centromere, providing biochemical confirmation of the point centromere model.","dates":{"release":"2012-01-01T00:00:00Z","publication":"2012 Apr","modification":"2025-04-25T23:16:05.827Z","creation":"2019-06-05T17:11:34Z"},"accession":"S-EPMC3316665","cross_references":{"pubmed":["22234856"],"doi":["10.1534/genetics.111.137711"]}}