{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["5"],"submitter":["Rodriguez Cristobal JJ"],"pubmed_abstract":["<h4>Background</h4>We have studied the possible effects of an intensive lifestyle change program on plasma fibrinogen levels, in patients with no cardiovascular disease, with elevated levels of fibrinogen, normal cholesterol levels, and a moderate estimated risk of coronary heart disease (CHD) and we have also analysed whether the effect on fibrinogen is independent of the effect on lipids.<h4>Results</h4>This clinical trial was controlled, unblinded and randomized, with parallel groups, done in 13 Basic Health Areas (BHA) in l'Hospitalet de Llobregat (Barcelona) and Barcelona city. The study included 436 patients, aged between 35 and 75 years, with no cardiovascular disease, elevated levels of fibrinogen (> 300 mg/dl), cholesterol < 250 mg/dl, 218 of whom received a more intensive interve"],"journal":["BMC research notes"],"pagination":["126"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC3317867"],"repository":["biostudies-literature"],"pubmed_title":["Randomised clinical trial of an intensive intervention in the primary care setting of patients with high plasma fibrinogen in the primary prevention of cardiovascular disease."],"pmcid":["PMC3317867"],"pubmed_authors":["Campinez Navarro M","Ortilles Tejera M","Pineiro Casaus M","Monge Escribano A","Comabella Cueco A","Corral Anton R","Gomez Moral MV","Merce Martorell G","Sanchez M","Fuentes Roldan C","Lopez Sanchez C","Mena Sanchez J","Ortega Abarca I","Isidro Barbero MT","Torres Segura M","Alvarez Rodriguez M","Perez Ganan M","Gasol Farga A","Gonzalez Burguillos MJ","Llaurado Sanclemente E","Garcia Gomila E","de Miguel Perez RM","Pena Sendra E","Marin Perales D","Montes Velayos R","Garcia Fuentes MM","Gutierrez Lengua R","Capdevila Fogues G","Ventura Albadalejo M","Ruso Bernardo T","Gil Colome AM","Moron Bermejo JR","Bonet Bernabeu A","Ballester Adell A","Pardo Escudero I","Leon Varo MD","Toledano Perez A","Riba Bellera L","Borrell Mestre MJ","Fernandez Esteve G","Sala Sastre A","Beltran E","Munoz Lloret A","Gavin Blasco I","Morillo Godoy C","Garcia Villaplana MI","Manzanares Janini A","Elias Hernandez M","Montserrat Vinals M","Gonzalez Rodriguez S","Payan Cruz M","Gonzalez Casado A","Gines I","Bonfill Gavalda M","Morgade Gonzalez S","Comelles Villalba M","Cano Lopez M","Santesmases Masana R","Gonzalez Diaz R","Mpa Sifuko Mdel C","de Mon er de Castellano A","Lamuedra Martinez MC","Fernandez MA","Morro Vevel MJ","Quillama Torres E","Velasco Vicente ME","Ubierna Gomez C","Botey Serrano A","Torralba Casado C","Calero Molina ME","Ramos Sanchez M","Munoz Castanedo MI","Mon Lopez E","Capillas Perez RM","Giro Molmer T","Gines Sanchez Y","Aranta Diaz A","Aliaga Ugarte M","Rodriguez Cristobal JJ","Mesa Aranda F","Rodriguez Perez A","Benavides F","Munoz Duque MC","Baullon Rodriguez M","Perea Martinez I","Escudero Hernandez M","Pujol Ramirez L","Liroz Navarro M","Valderas Sanchez MJ","Viloca Llobet MA","Daleo i Pibernat A","Barragan Brun N","Mejias Serrano T","Valbuena ME","Lopez Galan A","Llort Rane R","Gonzalez Perez C","Roig i Ribas G","Sole Sancho R","Jurado Vergara L","Mayta Taica JT","Abril Escusa E","Jimenez Leal R","Blasco Trabado A","Perez Alberti A","Fernandez Perez C","Rodriguez Lozano B","Delclos Baulies M","Boix Cervera C","Mendez Fernandez M","Gomez Navarro A","Arroyo Blesa F","Garcia Bonias D","Alvarez Castella M","Arevalo Garcia A","Benitez Camacho T","Martin Sierra C","Tarrago Espi P","Madico Cerezo MR","Fernandez Perez R","Ortiz Secanell R","Bosc M","Villafuerte Navarro P","Gutierrez Mesa S","Bielsa Alquezar M","Fuertes Rodriguez MT","Yrla Figueras RM","Palacios Teruel E","Esparrach Casasses M","Gonzalez Sierra A","Rodriguez Magallanes M","Fontoba Nadal E","Rochera Lopez O","Ferre Codina A","Martinez Pascual I","Martin Alvarez R","Solanes Casas M","Sanchez aragoza M","Gonzalez Nogales T","Romera Cabezas A","Castro Perez M","Alonso-Villaverde Grote C","Barnes Sanchez B","Benitez Saiz C","Trave Mercade P","Diez Tino AM","Fernandez Ruiz J","Roc Laborda M","Perez Santos JM","Luna Redondo G","Mene R","Llorens Martinez C","Gomez Escudero Y","Espinosa Y","Bleda Fernandez D","Medina Sacristan M","Cuesta Pipson MA","Freixas Pascual MJ","Cabre Aguilar V","Plaza Vicente MI","Jimenez-Fortin GT","Lopez Ojeda N","Herrador Delso E","aborda Lopez SL","Rilova Perez M","Sanchez Alvarez A","Blanco Rodriguez M","Guino Royo M","Pons Segales E","Sanchez Soro O","Martinez Carmona S","Malvas Garcia L","Lopez Perez E","Pablo Gil F","Gonzalez Sanchez MC","Peraferrer Puigpelet M","Contreras Garcia C","Paris Puigcerver G","Alegret M","Coma R","Crespo Lopez MR","Estrada V","EFAP group","Mendez-Aguirre Guitian M","Lopez Canfranc MC","Blasco Villanueva L","Serrano Demarco T","Villagrasa Romerales L","Aliguer Masramon ME"],"additional_accession":[]},"is_claimable":false,"name":"Randomised clinical trial of an intensive intervention in the primary care setting of patients with high plasma fibrinogen in the primary prevention of cardiovascular disease.","description":"<h4>Background</h4>We have studied the possible effects of an intensive lifestyle change program on plasma fibrinogen levels, in patients with no cardiovascular disease, with elevated levels of fibrinogen, normal cholesterol levels, and a moderate estimated risk of coronary heart disease (CHD) and we have also analysed whether the effect on fibrinogen is independent of the effect on lipids.<h4>Results</h4>This clinical trial was controlled, unblinded and randomized, with parallel groups, done in 13 Basic Health Areas (BHA) in l'Hospitalet de Llobregat (Barcelona) and Barcelona city. The study included 436 patients, aged between 35 and 75 years, with no cardiovascular disease, elevated levels of fibrinogen (> 300 mg/dl), cholesterol < 250 mg/dl, 218 of whom received a more intensive interve","dates":{"release":"2012-01-01T00:00:00Z","publication":"2012 Mar","modification":"2025-04-25T23:21:02.578Z","creation":"2019-03-27T00:51:52Z"},"accession":"S-EPMC3317867","cross_references":{"pubmed":["22381072"],"doi":["10.1186/1756-0500-5-126"]}}