{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Ling H"],"funding":["Medical Research Council","Wellcome Trust"],"pagination":["1141-53"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC3326257"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["135(Pt 4)"],"pubmed_abstract":["Repetitive finger tapping is commonly used to assess bradykinesia in Parkinson's disease. The Queen Square Brain Bank diagnostic criterion of Parkinson's disease defines bradykinesia as 'slowness of initiation with progressive reduction in speed and amplitude of repetitive action'. Although progressive supranuclear palsy is considered an atypical parkinsonian syndrome, it is not known whether patients with progressive supranuclear palsy have criteria-defined bradykinesia. This study objectively assessed repetitive finger tap performance and handwriting in patients with Parkinson's disease (n = 15), progressive supranuclear palsy (n = 9) and healthy age- and gender-matched controls (n = 16). The motion of the hand and digits was recorded in 3D during 15-s repetitive index finger-to-thumb ta"],"journal":["Brain : a journal of neurology"],"pubmed_title":["Hypokinesia without decrement distinguishes progressive supranuclear palsy from Parkinson's disease."],"pmcid":["PMC3326257"],"funding_grant_id":["084870/Z/08/Z","G0901503","G0501740"],"pubmed_authors":["Brown P","Ling H","Massey LA","Lees AJ","Day BL"],"additional_accession":[]},"is_claimable":false,"name":"Hypokinesia without decrement distinguishes progressive supranuclear palsy from Parkinson's disease.","description":"Repetitive finger tapping is commonly used to assess bradykinesia in Parkinson's disease. The Queen Square Brain Bank diagnostic criterion of Parkinson's disease defines bradykinesia as 'slowness of initiation with progressive reduction in speed and amplitude of repetitive action'. Although progressive supranuclear palsy is considered an atypical parkinsonian syndrome, it is not known whether patients with progressive supranuclear palsy have criteria-defined bradykinesia. This study objectively assessed repetitive finger tap performance and handwriting in patients with Parkinson's disease (n = 15), progressive supranuclear palsy (n = 9) and healthy age- and gender-matched controls (n = 16). The motion of the hand and digits was recorded in 3D during 15-s repetitive index finger-to-thumb ta","dates":{"release":"2012-01-01T00:00:00Z","publication":"2012 Apr","modification":"2025-07-06T03:04:31.676Z","creation":"2025-07-06T03:04:31.676Z"},"accession":"S-EPMC3326257","cross_references":{"pubmed":["22396397"],"doi":["10.1093/brain/aws038"]}}