biostudies-literatureUnknown68(Pt 4)Xie LThe title compound, C(51)H(78)N(4)O(12), is a derivative of rapamycin, a triene macrolide anti-biotic mol-ecule isolated from Streptomyces hygroscopicus. The macrocyclic ring structure has 15 chiral centres, with one of the substituent hy-droxy groups giving an intra-molecular hydrogen bond to a ketone O-atom acceptor. The mol-ecules also form inter-molecular hy-droxy-ketone O-H⋯O hydrogen-bonding associations, giving one-dimensional chains extending along (010). The crystal has 108 Å(3) solvent-accessible voids.Acta crystallographica. Section E, Structure reports onlineo1206-7https://www.ebi.ac.uk/biostudies/studies/S-EPMC3344143biostudies-literature41-Azido-41-de-oxy-rapamycin.PMC3344143Huang JZuo JXie LYu HCheng Yfalse41-Azido-41-de-oxy-rapamycin.The title compound, C(51)H(78)N(4)O(12), is a derivative of rapamycin, a triene macrolide anti-biotic mol-ecule isolated from Streptomyces hygroscopicus. The macrocyclic ring structure has 15 chiral centres, with one of the substituent hy-droxy groups giving an intra-molecular hydrogen bond to a ketone O-atom acceptor. The mol-ecules also form inter-molecular hy-droxy-ketone O-H⋯O hydrogen-bonding associations, giving one-dimensional chains extending along (010). The crystal has 108 Å(3) solvent-accessible voids.2012-01-01T00:00:00Z2012 Apr2025-04-04T09:12:34.617Z2019-03-27T00:53:04ZS-EPMC33441432260614610.1107/S1600536812012548