{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["7(5)"],"submitter":["Qin Y"],"pubmed_abstract":["Sequencing by Hybridization (SBH) reconstructs an n-long target DNA sequence from its biochemically determined l-long subsequences. In the standard approach, the length of a uniformly random sequence that can be unambiguously reconstructed is limited to n = O(2(l)) due to repetitive subsequences causing reconstruction degeneracies. We present a modified sequencing method that overcomes this limitation without the need for different types of biochemical assays and is robust to error."],"journal":["PloS one"],"pagination":["e35819"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC3344849"],"repository":["biostudies-literature"],"pubmed_title":["Sequencing by hybridization of long targets."],"pmcid":["PMC3344849"],"pubmed_authors":["Brenner MP","Schneider TM","Qin Y"],"additional_accession":[]},"is_claimable":false,"name":"Sequencing by hybridization of long targets.","description":"Sequencing by Hybridization (SBH) reconstructs an n-long target DNA sequence from its biochemically determined l-long subsequences. In the standard approach, the length of a uniformly random sequence that can be unambiguously reconstructed is limited to n = O(2(l)) due to repetitive subsequences causing reconstruction degeneracies. We present a modified sequencing method that overcomes this limitation without the need for different types of biochemical assays and is robust to error.","dates":{"release":"2012-01-01T00:00:00Z","publication":"2012","modification":"2026-04-30T18:59:43.293Z","creation":"2019-03-26T23:18:37Z"},"accession":"S-EPMC3344849","cross_references":{"pubmed":["22574124"],"doi":["10.1371/journal.pone.0035819"]}}