{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["7(5)"],"submitter":["Herold C"],"pubmed_abstract":["Dopamine D1-like receptors consist of D1 (D1A) and D5 (D1B) receptors and play a key role in working memory. However, their possibly differential contribution to working memory is unclear. We combined a working memory training protocol with a stepwise increase of cognitive subcomponents and real-time RT-PCR analysis of dopamine receptor expression in pigeons to identify molecular changes that accompany training of isolated cognitive subfunctions. In birds, the D1-like receptor family is extended and consists of the D1A, D1B, and D1D receptors. Our data show that D1B receptor plasticity follows a training that includes active mental maintenance of information, whereas D1A and D1D receptor plasticity in addition accompanies learning of stimulus-response associations. Plasticity of D1-like re"],"journal":["PloS one"],"pagination":["e36484"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC3344878"],"repository":["biostudies-literature"],"pubmed_title":["Plasticity in D1-like receptor expression is associated with different components of cognitive processes."],"pmcid":["PMC3344878"],"pubmed_authors":["Herold C","Joshi I","Hollmann M","Gunturkun O","Chehadi O"],"additional_accession":[]},"is_claimable":false,"name":"Plasticity in D1-like receptor expression is associated with different components of cognitive processes.","description":"Dopamine D1-like receptors consist of D1 (D1A) and D5 (D1B) receptors and play a key role in working memory. However, their possibly differential contribution to working memory is unclear. We combined a working memory training protocol with a stepwise increase of cognitive subcomponents and real-time RT-PCR analysis of dopamine receptor expression in pigeons to identify molecular changes that accompany training of isolated cognitive subfunctions. In birds, the D1-like receptor family is extended and consists of the D1A, D1B, and D1D receptors. Our data show that D1B receptor plasticity follows a training that includes active mental maintenance of information, whereas D1A and D1D receptor plasticity in addition accompanies learning of stimulus-response associations. Plasticity of D1-like re","dates":{"release":"2012-01-01T00:00:00Z","publication":"2012","modification":"2025-04-26T04:21:06.813Z","creation":"2019-03-26T23:18:37Z"},"accession":"S-EPMC3344878","cross_references":{"pubmed":["22574169"],"doi":["10.1371/journal.pone.0036484"]}}