{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["6(6)"],"submitter":["Whitehorn J"],"funding":["Wellcome Trust"],"pubmed_abstract":["Dengue is the most important arboviral infection of humans. Thrombocytopenia is frequently observed in the course of infection and haemorrhage may occur in severe disease. The degree of thrombocytopenia correlates with the severity of infection, and may contribute to the risk of haemorrhage. As a result of this prophylactic platelet transfusions are sometimes advocated for the prevention of haemorrhage. There is currently no evidence to support this practice, and platelet transfusions are costly and sometimes harmful. We conducted a global survey to assess the different approaches to the use of platelets in dengue. Respondents were all physicians involved with the treatment of patients with dengue. Respondents were asked that their answers reflected what they would do if they were the trea"],"journal":["PLoS neglected tropical diseases"],"pagination":["e1716"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC3383756"],"repository":["biostudies-literature"],"pubmed_title":["Prophylactic platelets in dengue: survey responses highlight lack of an evidence base."],"pmcid":["PMC3383756"],"pubmed_authors":["Larsson M","Peeling R","Bausch DG","Rodriguez Roche R","Thwaites G","Faiz A","Blumberg L","Horstick O","Nainggolan L","Dawurung J","Kroeger A","Simmons C","Sall A","Laksono IS","Guzman MG","Gomez WV","Wills B","Whitehorn J","Mishra A","Lum L","Borges A","Leo YS","Hien TT","Martinez E","Farrar J","Wertheim H"],"additional_accession":[]},"is_claimable":false,"name":"Prophylactic platelets in dengue: survey responses highlight lack of an evidence base.","description":"Dengue is the most important arboviral infection of humans. Thrombocytopenia is frequently observed in the course of infection and haemorrhage may occur in severe disease. The degree of thrombocytopenia correlates with the severity of infection, and may contribute to the risk of haemorrhage. As a result of this prophylactic platelet transfusions are sometimes advocated for the prevention of haemorrhage. There is currently no evidence to support this practice, and platelet transfusions are costly and sometimes harmful. We conducted a global survey to assess the different approaches to the use of platelets in dengue. Respondents were all physicians involved with the treatment of patients with dengue. Respondents were asked that their answers reflected what they would do if they were the trea","dates":{"release":"2012-01-01T00:00:00Z","publication":"2012","modification":"2026-07-15T18:43:06.26Z","creation":"2026-07-09T03:08:04.596Z"},"accession":"S-EPMC3383756","cross_references":{"pubmed":["22745847"],"doi":["10.1371/journal.pntd.0001716"]}}