{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["50(7)"],"submitter":["Posteraro B"],"pubmed_abstract":["We evaluated the usefulness of matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) for Cryptococcus identification at the species and subspecies levels by using an in-house database of 25 reference cryptococcal spectra. Eighty-one out of the 82 Cryptococcus isolates (72 Cryptococcus neoformans and 10 Cryptococcus gattii) tested were correctly identified with respect to their molecular type designations. We showed that MALDI-TOF MS is a practicable alternative to conventional mycology or DNA-based methods."],"journal":["Journal of clinical microbiology"],"pagination":["2472-6"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC3405602"],"repository":["biostudies-literature"],"pubmed_title":["Matrix-assisted laser desorption ionization-time of flight mass spectrometry-based method for discrimination between molecular types of Cryptococcus neoformans and Cryptococcus gattii."],"pmcid":["PMC3405602"],"pubmed_authors":["Tortorano AM","Posteraro P","Posteraro B","Cogliati M","Vella A","De Carolis E","Sanguinetti M","Florio AR"],"additional_accession":[]},"is_claimable":false,"name":"Matrix-assisted laser desorption ionization-time of flight mass spectrometry-based method for discrimination between molecular types of Cryptococcus neoformans and Cryptococcus gattii.","description":"We evaluated the usefulness of matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) for Cryptococcus identification at the species and subspecies levels by using an in-house database of 25 reference cryptococcal spectra. Eighty-one out of the 82 Cryptococcus isolates (72 Cryptococcus neoformans and 10 Cryptococcus gattii) tested were correctly identified with respect to their molecular type designations. We showed that MALDI-TOF MS is a practicable alternative to conventional mycology or DNA-based methods.","dates":{"release":"2012-01-01T00:00:00Z","publication":"2012 Jul","modification":"2021-02-26T08:43:15Z","creation":"2019-03-27T00:55:59Z"},"accession":"S-EPMC3405602","cross_references":{"pubmed":["22573595"],"doi":["10.1128/jcm.00737-12","10.1128/JCM.00737-12"]}}