biostudies-literatureUnknown50(10)Schaumburg FMethicillin-resistant Staphylococcus aureus (MRSA) originated from the health care setting but is now emerging in communities without health care contact (CA-MRSA) or in livestock (LA-MRSA). The impact on the whole MRSA population was assessed in a German prospective multicenter study. Thirty-three laboratories consecutively collected up to 50 MRSA isolates from infection or carriage during two sampling periods in 2004 to 2005 and 2010 to 2011. Patient-related data were collected using a standardized questionnaire. Methicillin resistance was confirmed by the detection of mecA or its homologue mecA(LGA251). The spa type and major virulence factors were analyzed for each isolate. In total, 1,604 (2004 to 2005) and 1,603 (2010 to 2011) MRSA isolates were analyzed; one isolate from each sampliJournal of clinical microbiology3186-92https://www.ebi.ac.uk/biostudies/studies/S-EPMC3457438biostudies-literaturePopulation dynamics among methicillin-resistant Staphylococcus aureus isolates in Germany during a 6-year period.PMC3457438Pfister WLucking CPeters GGatermann SWullenweber JMuller SH -U Borg KHoffler USimon VWurstl BReinert RSchubert SRissland JSchoerner CFinzer PSchmidt Wieland TSchwegmann Kvon Eiff CTrautmann MKalka-Moll WFrank UHerrmann MBar WErichsen HRohr UFrosch MMack DKaase MBuhrlen UKorber-Irrgang BScherpe Svan der Linden MKnobloch JKriegeskorte AAnders AJacobs EMonecke SFunke GUllmann UDiaz CVogt MFreytag CGeisen Jvon Muller LBecker KHell WRoggenkamp ARichter LFriedrich AWJonas DStraube EZollner BKresken MWichelhaus TSchade SSchwarz RMuller-Chorus AReiter WVogel ULommel ANoldt KRosenthal EKock RAbele-Horn MDitzen Astudy groupHasenberg FDobonici MWimmer-Dahmen MSeifert HRegnath TJansen BMellmann AEigner USchaumburg Fvon Wulffen HBierbaum GKaulfers MBeyreiß BAlbert FFahr AfalsePopulation dynamics among methicillin-resistant Staphylococcus aureus isolates in Germany during a 6-year period.Methicillin-resistant Staphylococcus aureus (MRSA) originated from the health care setting but is now emerging in communities without health care contact (CA-MRSA) or in livestock (LA-MRSA). The impact on the whole MRSA population was assessed in a German prospective multicenter study. Thirty-three laboratories consecutively collected up to 50 MRSA isolates from infection or carriage during two sampling periods in 2004 to 2005 and 2010 to 2011. Patient-related data were collected using a standardized questionnaire. Methicillin resistance was confirmed by the detection of mecA or its homologue mecA(LGA251). The spa type and major virulence factors were analyzed for each isolate. In total, 1,604 (2004 to 2005) and 1,603 (2010 to 2011) MRSA isolates were analyzed; one isolate from each sampli2012-01-01T00:00:00Z2012 Oct2025-04-04T12:04:35.63Z2019-03-27T00:58:20ZS-EPMC34574382281446410.1128/jcm.01174-1210.1128/JCM.01174-12