{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["7(9)"],"submitter":["Saroussi S"],"pubmed_abstract":["A ring of 8-15 identical c-subunits is essential for ion-translocation by the rotary electromotor of the ubiquitous F(O)F(1)-ATPase. Here we present the crystal structure at 3.4Å resolution of the c-ring from chloroplasts of a higher plant (Pisum sativum), determined using a native preparation. The crystal structure was found to resemble that of an (ancestral) cyanobacterium. Using elastic network modeling to investigate the ring's eigen-modes, we found five dominant modes of motion that fell into three classes. They revealed the following deformations of the ring: (I) ellipsoidal, (II) opposite twisting of the luminal circular surface of the ring against the stromal surface, and (III) kinking of the hairpin-shaped monomers in the middle, resulting in bending/stretching of the ring. Extens"],"journal":["PloS one"],"pagination":["e43045"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC3458034"],"repository":["biostudies-literature"],"pubmed_title":["Structure and flexibility of the C-ring in the electromotor of rotary F(0)F(1)-ATPase of pea chloroplasts."],"pmcid":["PMC3458034"],"pubmed_authors":["Schushan M","Saroussi S","Junge W","Ben-Tal N","Nelson N"],"additional_accession":[]},"is_claimable":false,"name":"Structure and flexibility of the C-ring in the electromotor of rotary F(0)F(1)-ATPase of pea chloroplasts.","description":"A ring of 8-15 identical c-subunits is essential for ion-translocation by the rotary electromotor of the ubiquitous F(O)F(1)-ATPase. Here we present the crystal structure at 3.4Å resolution of the c-ring from chloroplasts of a higher plant (Pisum sativum), determined using a native preparation. The crystal structure was found to resemble that of an (ancestral) cyanobacterium. Using elastic network modeling to investigate the ring's eigen-modes, we found five dominant modes of motion that fell into three classes. They revealed the following deformations of the ring: (I) ellipsoidal, (II) opposite twisting of the luminal circular surface of the ring against the stromal surface, and (III) kinking of the hairpin-shaped monomers in the middle, resulting in bending/stretching of the ring. Extens","dates":{"release":"2012-01-01T00:00:00Z","publication":"2012","modification":"2026-05-01T20:00:48.836Z","creation":"2019-03-26T23:19:01Z"},"accession":"S-EPMC3458034","cross_references":{"pubmed":["23049735"],"doi":["10.1371/journal.pone.0043045"]}}