{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["7(10)"],"submitter":["Wang CR"],"pubmed_abstract":["The neglected blood flukes Orientobilharzia spp. belonging to the Platyhelminthes, infect animals in a number of countries of the world, and cause cercarial dermatitis in humans, as well as significant diseases and even death in economically-important animals. MicroRNAs (miRNAs) are now considered to be a key mechanism of gene regulation. Herein, we investigated the global miRNA expression profile of adult O. turkestanicum using next-generation sequencing technology and real-time quantitative PCR, to gain further information on the role of these molecules in host invasion and the parasitic lifestyle of this species. A total of 13.48 million high quality reads were obtained out of 13.78 million raw sequencing reads, with 828 expressed miRNAs identified. Phylogenetic analysis showed that the"],"journal":["PloS one"],"pagination":["e47001"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC3468544"],"repository":["biostudies-literature"],"pubmed_title":["Characterization of microRNAs from Orientobilharzia turkestanicum, a neglected blood fluke of human and animal health significance."],"pmcid":["PMC3468544"],"pubmed_authors":["Nisbet AJ","Zhu XQ","Chang QC","Huang SY","Zhou DH","Zou FC","Wang CR","Xu MJ","Fu JH"],"additional_accession":[]},"is_claimable":false,"name":"Characterization of microRNAs from Orientobilharzia turkestanicum, a neglected blood fluke of human and animal health significance.","description":"The neglected blood flukes Orientobilharzia spp. belonging to the Platyhelminthes, infect animals in a number of countries of the world, and cause cercarial dermatitis in humans, as well as significant diseases and even death in economically-important animals. MicroRNAs (miRNAs) are now considered to be a key mechanism of gene regulation. Herein, we investigated the global miRNA expression profile of adult O. turkestanicum using next-generation sequencing technology and real-time quantitative PCR, to gain further information on the role of these molecules in host invasion and the parasitic lifestyle of this species. A total of 13.48 million high quality reads were obtained out of 13.78 million raw sequencing reads, with 828 expressed miRNAs identified. Phylogenetic analysis showed that the","dates":{"release":"2012-01-01T00:00:00Z","publication":"2012","modification":"2026-04-16T05:20:33.106Z","creation":"2026-04-07T14:07:26.389Z"},"accession":"S-EPMC3468544","cross_references":{"pubmed":["23071694"],"doi":["10.1371/journal.pone.0047001"]}}