biostudies-literatureUnknown68(Pt 10)Jin SDuring the recrystallization of 3-[4-(2-carb-oxy-eth-yl)piperazin-1-yl]propionic acid, the carb-oxy-lic acid H atoms were transferred to the piperazine N atoms, forming the title compound, C(10)H(18)N(2)O(4)·2H(2)O, in which the zwitterion lies about an inversion center. In the crystal, bifurcated N-H⋯(O,O) hydrogen bonds connect the zwitterions into a two-dimensional framework parallel to (-102) forming R(4) (4)(30) rings. O-H⋯O hydrogen bonds involving the solvent water mol-ecules connect the two-dimensional framework into a three-dimensional network. In addition, weak C-H⋯O hydrogen bonds are observed.Acta crystallographica. Section E, Structure reports onlineo2827https://www.ebi.ac.uk/biostudies/studies/S-EPMC3470189biostudies-literature3,3'-(Piperazine-1,4-diium-1,4-di-yl)di-propionate dihydrate.PMC3470189Fang HHuang YJin SWang TDing Lfalse3,3'-(Piperazine-1,4-diium-1,4-di-yl)di-propionate dihydrate.During the recrystallization of 3-[4-(2-carb-oxy-eth-yl)piperazin-1-yl]propionic acid, the carb-oxy-lic acid H atoms were transferred to the piperazine N atoms, forming the title compound, C(10)H(18)N(2)O(4)·2H(2)O, in which the zwitterion lies about an inversion center. In the crystal, bifurcated N-H⋯(O,O) hydrogen bonds connect the zwitterions into a two-dimensional framework parallel to (-102) forming R(4) (4)(30) rings. O-H⋯O hydrogen bonds involving the solvent water mol-ecules connect the two-dimensional framework into a three-dimensional network. In addition, weak C-H⋯O hydrogen bonds are observed.2012-01-01T00:00:00Z2012 Oct2025-04-19T15:52:53.588Z2019-03-27T00:59:01ZS-EPMC34701892312563310.1107/S1600536812037312