<HashMap><database>biostudies-literature</database><scores/><additional><omics_type>Unknown</omics_type><volume>68(Pt 10)</volume><submitter>Kumar M</submitter><pubmed_abstract>In the title compound, C(23)H(25)BrN(4)O(3)S(2), the benzene rings bridged by the sulfonamide group are tilted relative to each other by 69.7 (1)° and the dihedral angle between the sulfur-bridged pyrimidine and benzene rings is 70.4 (1)°. The mol-ecular conformation is stabilized by a weak intra-molecular π-π stacking inter-action between the pyrimidine and the 4-methyl benzene rings [centroid-centroid distance = 3.633 (2) Å]. The piperidine ring adopts a chair conformation. In the crystal, mol-ecules are linked into inversion dimers by pairs of N-H⋯O hydrogen bonds.</pubmed_abstract><journal>Acta crystallographica. Section E, Structure reports online</journal><pagination>o2831</pagination><full_dataset_link>https://www.ebi.ac.uk/biostudies/studies/S-EPMC3470193</full_dataset_link><repository>biostudies-literature</repository><pubmed_title>N-(2-{[5-Bromo-2-(piperidin-1-yl)pyrimidin-4-yl]sulfan-yl}-4-meth-oxy-phen-yl)-4-methyl-benzene-sulfonamide.</pubmed_title><pmcid>PMC3470193</pmcid><pubmed_authors>Kapoor K</pubmed_authors><pubmed_authors>Sridhar MA</pubmed_authors><pubmed_authors>Mallesha L</pubmed_authors><pubmed_authors>Kant R</pubmed_authors><pubmed_authors>Kumar M</pubmed_authors><pubmed_authors>Gupta VK</pubmed_authors></additional><is_claimable>false</is_claimable><name>N-(2-{[5-Bromo-2-(piperidin-1-yl)pyrimidin-4-yl]sulfan-yl}-4-meth-oxy-phen-yl)-4-methyl-benzene-sulfonamide.</name><description>In the title compound, C(23)H(25)BrN(4)O(3)S(2), the benzene rings bridged by the sulfonamide group are tilted relative to each other by 69.7 (1)° and the dihedral angle between the sulfur-bridged pyrimidine and benzene rings is 70.4 (1)°. The mol-ecular conformation is stabilized by a weak intra-molecular π-π stacking inter-action between the pyrimidine and the 4-methyl benzene rings [centroid-centroid distance = 3.633 (2) Å]. The piperidine ring adopts a chair conformation. In the crystal, mol-ecules are linked into inversion dimers by pairs of N-H⋯O hydrogen bonds.</description><dates><release>2012-01-01T00:00:00Z</release><publication>2012 Oct</publication><modification>2025-04-19T15:53:02.774Z</modification><creation>2019-03-27T00:59:01Z</creation></dates><accession>S-EPMC3470193</accession><cross_references><pubmed>23125637</pubmed><doi>10.1107/S1600536812037257</doi></cross_references></HashMap>