{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Lo W"],"funding":["NIGMS NIH HHS"],"pagination":["9883-92"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC3483649"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["51(18)"],"pubmed_abstract":["The formation and solution properties, including stability in mixed aqueous-Me(2)SO media, have been investigated for an [Fe(4)S(4)](2+) cluster derived from β-cyclodextrin (CD) dithiolate. Clusters of the type [Fe(4)S(4)(SAr)(4)](2-) (Ar = Ph, C(6)H(4)-3-F) are generated in Me(2)SO by redox reactions of [Fe(4)S(4)(SEt)(4)](2-) with 2 equiv of ArSSAr. An analogous reaction with the intramolecular disulfide of 6(A),6(D)-(3-NHCOC(6)H(4)-1-SH)(2)-6(A),6(D)-dideoxy-β-cyclodextrin (14), whose synthesis is described, affords a completely substituted cluster formulated as [Fe(4)S(4){β-CD-(1,3-NHCOC(6)H(4)S)(2)}(2)](2-) (15). Ligand binding is indicated by a circular dichroism spectrum and also by UV-visible and isotropically shifted (1)H NMR spectra and redox behavior convincingly similar to [Fe("],"journal":["Inorganic chemistry"],"pubmed_title":["Formation, spectroscopic characterization, and solution stability of an [Fe4S4]2+ cluster derived from β-cyclodextrin dithiolate."],"pmcid":["PMC3483649"],"funding_grant_id":["R37 GM028856","GM28856","R01 GM028856"],"pubmed_authors":["Holm RH","Huang S","Ling CC","Lo W","Zhang P"],"additional_accession":[]},"is_claimable":false,"name":"Formation, spectroscopic characterization, and solution stability of an [Fe4S4]2+ cluster derived from β-cyclodextrin dithiolate.","description":"The formation and solution properties, including stability in mixed aqueous-Me(2)SO media, have been investigated for an [Fe(4)S(4)](2+) cluster derived from β-cyclodextrin (CD) dithiolate. Clusters of the type [Fe(4)S(4)(SAr)(4)](2-) (Ar = Ph, C(6)H(4)-3-F) are generated in Me(2)SO by redox reactions of [Fe(4)S(4)(SEt)(4)](2-) with 2 equiv of ArSSAr. An analogous reaction with the intramolecular disulfide of 6(A),6(D)-(3-NHCOC(6)H(4)-1-SH)(2)-6(A),6(D)-dideoxy-β-cyclodextrin (14), whose synthesis is described, affords a completely substituted cluster formulated as [Fe(4)S(4){β-CD-(1,3-NHCOC(6)H(4)S)(2)}(2)](2-) (15). Ligand binding is indicated by a circular dichroism spectrum and also by UV-visible and isotropically shifted (1)H NMR spectra and redox behavior convincingly similar to [Fe(","dates":{"release":"2012-01-01T00:00:00Z","publication":"2012 Sep","modification":"2025-04-05T12:54:51.263Z","creation":"2019-03-27T00:59:39Z"},"accession":"S-EPMC3483649","cross_references":{"pubmed":["22934734"],"doi":["10.1021/ic301324u"]}}