{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["8"],"submitter":["Tigchelaar A"],"pubmed_abstract":["Iridium-catalyzed intramolecular [4 + 2] cycloadditions of diene-tethered alkynyl halides were investigated by using [IrCl(cod)](2) as catalyst, and dppe was found to be the most suitable phosphine ligand for the reaction. No oxidative insertion of the iridium into the carbon-halide bond was observed, and the reactions proceeded to provide the halogenated cycloadducts in good yield (75-94%). These results are the first examples of cycloadditions of alkynyl halides using an iridium catalyst."],"journal":["Beilstein journal of organic chemistry"],"pagination":["1765-70"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC3511010"],"repository":["biostudies-literature"],"pubmed_title":["Iridium-catalyzed intramolecular [4 + 2] cycloadditions of alkynyl halides."],"pmcid":["PMC3511010"],"pubmed_authors":["Tam W","Tigchelaar A"],"additional_accession":[]},"is_claimable":false,"name":"Iridium-catalyzed intramolecular [4 + 2] cycloadditions of alkynyl halides.","description":"Iridium-catalyzed intramolecular [4 + 2] cycloadditions of diene-tethered alkynyl halides were investigated by using [IrCl(cod)](2) as catalyst, and dppe was found to be the most suitable phosphine ligand for the reaction. No oxidative insertion of the iridium into the carbon-halide bond was observed, and the reactions proceeded to provide the halogenated cycloadducts in good yield (75-94%). These results are the first examples of cycloadditions of alkynyl halides using an iridium catalyst.","dates":{"release":"2012-01-01T00:00:00Z","publication":"2012","modification":"2025-05-18T10:44:56.302Z","creation":"2025-05-18T10:44:56.302Z"},"accession":"S-EPMC3511010","cross_references":{"pubmed":["23209510"],"doi":["10.3762/bjoc.8.201"]}}