biostudies-literatureAjami NJNIDDK NIH HHSNCRR NIH HHSNIAID NIH HHS1980-3https://www.ebi.ac.uk/biostudies/studies/S-EPMC3535860biostudies-literatureUnknown19(12)An assay was developed to detect antibodies against two norovirus proteases among participants in a Norwalk virus (GI.1) challenge study. Prechallenge seroprevalence was lower against the protease from the homologous GI.1 virus than against protease from a heterologous GII.4 strain. Seroresponses were detected for 14 of 19 (74%) infected persons.Clinical and vaccine immunology : CVIAntibody responses to norovirus genogroup GI.1 and GII.4 proteases in volunteers administered Norwalk virus.PMC3535860P30 DK56336P30 DK056338P01 AI 57788M01 RR-000188P30 DK056336N01 AI025465M01 RR000188P01 AI057788Opekun ARNeill FHCarrillo BMuhaxhiri ZAtmar RLGilger MAGraham DYEstes MKBarry MAPrasad BVAjami NJfalseAntibody responses to norovirus genogroup GI.1 and GII.4 proteases in volunteers administered Norwalk virus.An assay was developed to detect antibodies against two norovirus proteases among participants in a Norwalk virus (GI.1) challenge study. Prechallenge seroprevalence was lower against the protease from the homologous GI.1 virus than against protease from a heterologous GII.4 strain. Seroresponses were detected for 14 of 19 (74%) infected persons.2012-01-01T00:00:00Z2012 Dec2021-02-20T04:59:47Z2019-03-27T01:02:34ZS-EPMC35358602303517710.1128/CVI.00411-1210.1128/cvi.00411-12