biostudies-literatureUnknown22(1)Kong WLTwo swine influenza (SI) H1N1 virus was isolated from a pig during a severe outbreak of respiratory disease in south China. The two H1N1 influenza viruses were classical SI virus. A/swine/Guangdong/L6/09 is classical SI virus of recent years, which is of the main SI virus in China. Howere, A/swine/Guangdong/L3/09 was closet to A/swine/Iowa/1931, which was the first isolated SI virus and had demonstrated significant pathogenicity in animal models. The results of phylogenetic analysis of A/swine/Guangdong/L3/09 showed a close relationship with the 1918 pandemic virus. The results suggested that the previous SI virus appeared again. Whether, it brought a new pandemic to pigs deserves more attention.Indian journal of virology : an official organ of Indian Virological Society66-71https://www.ebi.ac.uk/biostudies/studies/S-EPMC3550729biostudies-literatureIsolation and Phylogenetic Analysis of H1N1 Swine Influenza Virus from Sick Pigs in Southern China.PMC3550729Huang LZZhang GHQi HTKong WLCao NZhao FRHuang YMZhao MMQi WBJiao PRGuan SSWang WHfalseIsolation and Phylogenetic Analysis of H1N1 Swine Influenza Virus from Sick Pigs in Southern China.Two swine influenza (SI) H1N1 virus was isolated from a pig during a severe outbreak of respiratory disease in south China. The two H1N1 influenza viruses were classical SI virus. A/swine/Guangdong/L6/09 is classical SI virus of recent years, which is of the main SI virus in China. Howere, A/swine/Guangdong/L3/09 was closet to A/swine/Iowa/1931, which was the first isolated SI virus and had demonstrated significant pathogenicity in animal models. The results of phylogenetic analysis of A/swine/Guangdong/L3/09 showed a close relationship with the 1918 pandemic virus. The results suggested that the previous SI virus appeared again. Whether, it brought a new pandemic to pigs deserves more attention.2011-01-01T00:00:00Z2011 Jun2024-11-21T02:09:28.553Z2019-03-27T01:03:35ZS-EPMC35507292363750510.1007/s13337-011-0035-2