{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Contreras EQ"],"funding":["NHGRI NIH HHS"],"pagination":["1148-54"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC3556816"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["47(2)"],"pubmed_abstract":["To fully understand the biological and environmental impacts of nanomaterials requires studies that address both sublethal end points and multigenerational effects. Here, we use a nematode to examine these issues as they relate to exposure to two different types of quantum dots, core (CdSe) and core-shell (CdSe/ZnS), and to compare the effect to those observed after cadmium salt exposures. The strong fluorescence of the core-shell QDs allowed for the direct visualization of the materials in the digestive track within a few hours of exposure. Multiple end points, including both developmental and locomotive, were examined at QD exposures of low (10 mg/L Cd), medium (50 mg/L Cd), and high concentrations (100 mg/L Cd). While the core-shell QDs showed no effect on fitness (lifespan, fertility, "],"journal":["Environmental science & technology"],"pubmed_title":["Toxicity of quantum dots and cadmium salt to Caenorhabditis elegans after multigenerational exposure."],"pmcid":["PMC3556816"],"funding_grant_id":["R00 HG004724","R00HG004724"],"pubmed_authors":["Escalera G","Contreras EQ","Cho M","Zhong W","Colvin VL","Zhu H","Puppala HL"],"additional_accession":[]},"is_claimable":false,"name":"Toxicity of quantum dots and cadmium salt to Caenorhabditis elegans after multigenerational exposure.","description":"To fully understand the biological and environmental impacts of nanomaterials requires studies that address both sublethal end points and multigenerational effects. Here, we use a nematode to examine these issues as they relate to exposure to two different types of quantum dots, core (CdSe) and core-shell (CdSe/ZnS), and to compare the effect to those observed after cadmium salt exposures. The strong fluorescence of the core-shell QDs allowed for the direct visualization of the materials in the digestive track within a few hours of exposure. Multiple end points, including both developmental and locomotive, were examined at QD exposures of low (10 mg/L Cd), medium (50 mg/L Cd), and high concentrations (100 mg/L Cd). While the core-shell QDs showed no effect on fitness (lifespan, fertility, ","dates":{"release":"2013-01-01T00:00:00Z","publication":"2013 Jan","modification":"2025-04-26T10:46:46Z","creation":"2019-03-27T01:03:53Z"},"accession":"S-EPMC3556816","cross_references":{"pubmed":["23241207"],"doi":["10.1021/es3036785"]}}