{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Srikuea R"],"funding":["NCATS NIH HHS","NIA NIH HHS"],"pagination":["519-28"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC3558634"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["65(2)"],"pubmed_abstract":["<h4>Objective</h4>To identify muscle physiologic properties that may contribute to postexertional fatigue and malaise in women with fibromyalgia (FM).<h4>Methods</h4>Healthy postmenopausal women with (n = 11) and without (n = 11) FM, ages 51-70 years, participated in this study. Physical characteristics and responses to self-reported questionnaires were evaluated. Strength loss and tissue oxygenation in response to a fatiguing exercise protocol were used to quantify fatigability and the local muscle hemodynamic profile. Muscle biopsies were performed to assess between-group differences in baseline muscle properties using histochemical, immunohistochemical, and electron microscopic analyses.<h4>Results</h4>There was no significant difference between healthy controls and FM patients in muscl"],"journal":["Arthritis and rheumatism"],"pubmed_title":["Association of fibromyalgia with altered skeletal muscle characteristics which may contribute to postexertional fatigue in postmenopausal women."],"pmcid":["PMC3558634"],"funding_grant_id":["UL1 TR001998","R21-AG-34279","UL1 TR000117","R21 AG034279","UL1-TR-000117"],"pubmed_authors":["Crofford LJ","Symons TB","Lee JD","Peterson CA","Long DE","Chomentowski PJ","Srikuea R","Shang Y","Yu G"],"additional_accession":[]},"is_claimable":false,"name":"Association of fibromyalgia with altered skeletal muscle characteristics which may contribute to postexertional fatigue in postmenopausal women.","description":"<h4>Objective</h4>To identify muscle physiologic properties that may contribute to postexertional fatigue and malaise in women with fibromyalgia (FM).<h4>Methods</h4>Healthy postmenopausal women with (n = 11) and without (n = 11) FM, ages 51-70 years, participated in this study. Physical characteristics and responses to self-reported questionnaires were evaluated. Strength loss and tissue oxygenation in response to a fatiguing exercise protocol were used to quantify fatigability and the local muscle hemodynamic profile. Muscle biopsies were performed to assess between-group differences in baseline muscle properties using histochemical, immunohistochemical, and electron microscopic analyses.<h4>Results</h4>There was no significant difference between healthy controls and FM patients in muscl","dates":{"release":"2013-01-01T00:00:00Z","publication":"2013 Feb","modification":"2025-05-29T22:29:05.112Z","creation":"2019-03-27T01:04:02Z"},"accession":"S-EPMC3558634","cross_references":{"pubmed":["23124535"],"doi":["10.1002/art.37763"]}}