{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Richter HE"],"funding":["NIDDK NIH HHS"],"pagination":["485-9"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC3560926"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["188(2)"],"pubmed_abstract":["<h4>Purpose</h4>We examined preoperative and postoperative patient related factors associated with continence status up to 7 years after surgery for stress urinary incontinence.<h4>Materials and methods</h4>Women randomized to Burch colposuspension or fascial sling surgery and assessed for the primary outcome of urinary continence 2 years after surgery were eligible to enroll in a prospective observational study. Survival analysis was used to investigate baseline and postoperative factors in the subsequent risk of stress urinary incontinence, defined as self-report of stress urinary incontinence symptoms, incontinence episodes on a 3-day diary or surgical re-treatment.<h4>Results</h4>Of the women who participated in the randomized trial 74% (482 of 655) were enrolled in the followup study. Urinary continence rates decreased during a period of 2 to 7 years postoperatively from 42% to 13% in the Burch group and from 52% to 27% in the sling group, respectively. Among the baseline factors included in the first multivariable model age (p = 0.03), prior stress urinary incontinence surgery (p = 0.02), menopausal status (0.005), urge index (0.006), assigned surgery (p = 0.01) and recruiting site (p = 0.02) were independently associated with increased risk of incontinence. In the final multivariable model including baseline and postoperative factors, Burch surgery (p = 0.01), baseline variables of prior urinary incontinence surgery (p = 0.04), menopausal status (p = 0.03) and postoperative urge index (p <0.001) were each significantly associated with a greater risk of recurrent urinary incontinence.<h4>Conclusions</h4>Preoperative and postoperative urgency incontinence symptoms, Burch urethropexy, prior stress urinary incontinence surgery and menopausal status were negatively associated with long-term continence rates. More effective treatment of urgency urinary incontinence in patients who undergo stress urinary incontinence surgery may improve long-term overall continence status."],"journal":["The Journal of urology"],"pubmed_title":["Patient related factors associated with long-term urinary continence after Burch colposuspension and pubovaginal fascial sling surgeries."],"pmcid":["PMC3560926"],"funding_grant_id":["U01 DK60397","U01 DK060393","U01 DK60395","U01 DK060395","U01 DK058231","U01 DK58234","U01 DK60393","U01 DK60380","U01 DK060380","U01 DK58231","U01 DK060401","U01 DK060379","U01 DK60401","U01 DK60379","U01 DK060397","U01 DK058225","U01 DK58225","U01 DK058234","U01 DK058229","U01 DK58229"],"pubmed_authors":["Zyczynski HM","Chai TC","Urinary Incontinence Treatment Network","Kraus SR","Brubaker L","Kusek JW","Richter HE","Zimmern P","Gormley EA","Albo ME","Sirls LT","Norton P","Stoddard AM","Xu Y"],"additional_accession":[]},"is_claimable":false,"name":"Patient related factors associated with long-term urinary continence after Burch colposuspension and pubovaginal fascial sling surgeries.","description":"<h4>Purpose</h4>We examined preoperative and postoperative patient related factors associated with continence status up to 7 years after surgery for stress urinary incontinence.<h4>Materials and methods</h4>Women randomized to Burch colposuspension or fascial sling surgery and assessed for the primary outcome of urinary continence 2 years after surgery were eligible to enroll in a prospective observational study. Survival analysis was used to investigate baseline and postoperative factors in the subsequent risk of stress urinary incontinence, defined as self-report of stress urinary incontinence symptoms, incontinence episodes on a 3-day diary or surgical re-treatment.<h4>Results</h4>Of the women who participated in the randomized trial 74% (482 of 655) were enrolled in the followup study. Urinary continence rates decreased during a period of 2 to 7 years postoperatively from 42% to 13% in the Burch group and from 52% to 27% in the sling group, respectively. Among the baseline factors included in the first multivariable model age (p = 0.03), prior stress urinary incontinence surgery (p = 0.02), menopausal status (0.005), urge index (0.006), assigned surgery (p = 0.01) and recruiting site (p = 0.02) were independently associated with increased risk of incontinence. In the final multivariable model including baseline and postoperative factors, Burch surgery (p = 0.01), baseline variables of prior urinary incontinence surgery (p = 0.04), menopausal status (p = 0.03) and postoperative urge index (p <0.001) were each significantly associated with a greater risk of recurrent urinary incontinence.<h4>Conclusions</h4>Preoperative and postoperative urgency incontinence symptoms, Burch urethropexy, prior stress urinary incontinence surgery and menopausal status were negatively associated with long-term continence rates. More effective treatment of urgency urinary incontinence in patients who undergo stress urinary incontinence surgery may improve long-term overall continence status.","dates":{"release":"2012-01-01T00:00:00Z","publication":"2012 Aug","modification":"2024-11-12T11:06:27.682Z","creation":"2019-03-26T23:05:14Z"},"accession":"S-EPMC3560926","cross_references":{"pubmed":["22704099"],"doi":["10.1016/j.juro.2012.04.010"]}}