biostudies-literatureHalfdanarson TRNIDDK NIH HHSNIAID NIH HHS1042-7https://www.ebi.ac.uk/biostudies/studies/S-EPMC3594736biostudies-literatureUnknown8(12)<h4>Background & aims</h4>Celiac disease (CD) is associated with an increased risk of lymphoma. However, relatively few studies have assessed the outcome of patients diagnosed with both CD and lymphoma. We evaluated the temporal association between lymphoma and CD, along with clinical presentation, response to therapy, and prognosis.<h4>Methods</h4>Patients diagnosed with both CD and lymphoma were identified retrospectively in a tertiary referral center. Clinical characteristics and survival were analyzed.<h4>Results</h4>Sixty-three patients (36 men) were identified who had been diagnosed with lymphoma and CD. Thirty-six (57%) were diagnosed with CD before they were diagnosed with lymphoma. The most common histologic entity was diffuse, large, B-cell lymphoma, which affected 18 (29%) patieClinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological AssociationPatients with celiac disease and B-cell lymphoma have a better prognosis than those with T-cell lymphoma.PMC3594736R01 DK057892T32 AI007047DK-57892T32 AI-07047Habermann TMRubio-Tapia AHalfdanarson TRRistow KMMurray JAInwards DJfalsePatients with celiac disease and B-cell lymphoma have a better prognosis than those with T-cell lymphoma.<h4>Background & aims</h4>Celiac disease (CD) is associated with an increased risk of lymphoma. However, relatively few studies have assessed the outcome of patients diagnosed with both CD and lymphoma. We evaluated the temporal association between lymphoma and CD, along with clinical presentation, response to therapy, and prognosis.<h4>Methods</h4>Patients diagnosed with both CD and lymphoma were identified retrospectively in a tertiary referral center. Clinical characteristics and survival were analyzed.<h4>Results</h4>Sixty-three patients (36 men) were identified who had been diagnosed with lymphoma and CD. Thirty-six (57%) were diagnosed with CD before they were diagnosed with lymphoma. The most common histologic entity was diffuse, large, B-cell lymphoma, which affected 18 (29%) patie2010-01-01T00:00:00Z2010 Dec2025-04-19T09:55:51.301Z2019-03-26T23:06:36ZS-EPMC35947362085121010.1016/j.cgh.2010.09.007