{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["13"],"submitter":["da Silva ER"],"pubmed_abstract":["<h4>Background</h4>Lower respiratory tract infection (LRTI) is a major cause of pediatric morbidity and mortality, especially among non-affluent communities. In this study we determine the impact of respiratory viruses and how viral co-detections/infections can affect clinical LRTI severity in children in a hospital setting.<h4>Methods</h4>Patients younger than 3 years of age admitted to a tertiary hospital in Brazil during the months of high prevalence of respiratory viruses had samples collected from nasopharyngeal aspiration. These samples were tested for 13 different respiratory viruses through real-time PCR (rt-PCR). Patients were followed during hospitalization, and clinical data and population characteristics were collected during that period and at discharge to evaluate severity ma"],"journal":["BMC infectious diseases"],"pagination":["41"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC3598993"],"repository":["biostudies-literature"],"pubmed_title":["Severe lower respiratory tract infection in infants and toddlers from a non-affluent population: viral etiology and co-detection as risk factors."],"pmcid":["PMC3598993"],"pubmed_authors":["Cintra O","da Silva ER","Stein RT","Mattiello R","Jones MH","de Paula FE","Delcaro LS","Ribeiro JD","Pitrez MC","Proenca-Modena JL","Arruda E","Sarria EE"],"additional_accession":[]},"is_claimable":false,"name":"Severe lower respiratory tract infection in infants and toddlers from a non-affluent population: viral etiology and co-detection as risk factors.","description":"<h4>Background</h4>Lower respiratory tract infection (LRTI) is a major cause of pediatric morbidity and mortality, especially among non-affluent communities. In this study we determine the impact of respiratory viruses and how viral co-detections/infections can affect clinical LRTI severity in children in a hospital setting.<h4>Methods</h4>Patients younger than 3 years of age admitted to a tertiary hospital in Brazil during the months of high prevalence of respiratory viruses had samples collected from nasopharyngeal aspiration. These samples were tested for 13 different respiratory viruses through real-time PCR (rt-PCR). Patients were followed during hospitalization, and clinical data and population characteristics were collected during that period and at discharge to evaluate severity ma","dates":{"release":"2013-01-01T00:00:00Z","publication":"2013 Jan","modification":"2026-07-15T17:32:09.54Z","creation":"2026-07-07T03:09:49.526Z"},"accession":"S-EPMC3598993","cross_references":{"pubmed":["23351117"],"doi":["10.1186/1471-2334-13-41"]}}