{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Carroll C"],"funding":["Medical Research Council"],"pagination":["497-505"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC3607262"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["15(4)"],"pubmed_abstract":["<h4>Background</h4>Apathy is associated with pervasive and disadvantageous effects on daily functioning. It has been observed transiently in some children after surgery for posterior fossa tumors. In this study, our objective was to examine prevalence, associations, and predictors of apathy in adult survivors of an infantile posterior fossa brain tumor (PFT).<h4>Methods</h4>One hundred seventeen adult survivors of a childhood PFT diagnosed before age 5 years and 60 of their siblings were assessed in a cross-sectional study a mean of 32 years (range, 18-53 years) after survivors' initial tumor diagnoses, using the Marin Apathy Evaluation Scale (AES), the Weschler Abbreviated Scale of Intelligence and the Composite International Diagnostic Interview for psychiatric disorders.<h4>Results</h4>"],"journal":["Neuro-oncology"],"pubmed_title":["Prevalence, associations, and predictors of apathy in adult survivors of infantile (<5 years of age) posterior fossa brain tumors."],"pmcid":["PMC3607262"],"funding_grant_id":["MC_U105579212"],"pubmed_authors":["Ring HA","Spoudeas HA","Hawkins MM","Watson P","Clare IC","Walker DA","Carroll C","Holland AJ"],"additional_accession":[]},"is_claimable":false,"name":"Prevalence, associations, and predictors of apathy in adult survivors of infantile (<5 years of age) posterior fossa brain tumors.","description":"<h4>Background</h4>Apathy is associated with pervasive and disadvantageous effects on daily functioning. It has been observed transiently in some children after surgery for posterior fossa tumors. In this study, our objective was to examine prevalence, associations, and predictors of apathy in adult survivors of an infantile posterior fossa brain tumor (PFT).<h4>Methods</h4>One hundred seventeen adult survivors of a childhood PFT diagnosed before age 5 years and 60 of their siblings were assessed in a cross-sectional study a mean of 32 years (range, 18-53 years) after survivors' initial tumor diagnoses, using the Marin Apathy Evaluation Scale (AES), the Weschler Abbreviated Scale of Intelligence and the Composite International Diagnostic Interview for psychiatric disorders.<h4>Results</h4>","dates":{"release":"2013-01-01T00:00:00Z","publication":"2013 Apr","modification":"2025-04-04T20:28:39.215Z","creation":"2019-03-27T01:06:35Z"},"accession":"S-EPMC3607262","cross_references":{"pubmed":["23502428"],"doi":["10.1093/neuonc/nos320"]}}