biostudies-literatureMenni CWellcome Trust506-514https://www.ebi.ac.uk/biostudies/studies/S-EPMC3608890biostudies-literatureUnknown9(2)Nutrition plays an important role in human metabolism and health. Metabolomics is a promising tool for clinical, genetic and nutritional studies. A key question is to what extent metabolomic profiles reflect nutritional patterns in an epidemiological setting. We assessed the relationship between metabolomic profiles and nutritional intake in women from a large cross-sectional community study. Food frequency questionnaires (FFQs) were applied to 1,003 women from the TwinsUK cohort with targeted metabolomic analyses of serum samples using the Biocrates Absolute-IDQ™ Kit p150 (163 metabolites). We analyzed seven nutritional parameters: coffee intake, garlic intake and nutritional scores derived from the FFQs summarizing fruit and vegetable intake, alcohol intake, meat intake, hypo-caloric dieMetabolomics : Official journal of the Metabolomic SocietyTargeted metabolomics profiles are strongly correlated with nutritional patterns in women.PMC3608890277849Valdes AMAdamski JZhai GRomisch-Margl WSpector TDPrehn CCassidy AMacgregor AMenni CIllig TSuhre KfalseTargeted metabolomics profiles are strongly correlated with nutritional patterns in women.Nutrition plays an important role in human metabolism and health. Metabolomics is a promising tool for clinical, genetic and nutritional studies. A key question is to what extent metabolomic profiles reflect nutritional patterns in an epidemiological setting. We assessed the relationship between metabolomic profiles and nutritional intake in women from a large cross-sectional community study. Food frequency questionnaires (FFQs) were applied to 1,003 women from the TwinsUK cohort with targeted metabolomic analyses of serum samples using the Biocrates Absolute-IDQ™ Kit p150 (163 metabolites). We analyzed seven nutritional parameters: coffee intake, garlic intake and nutritional scores derived from the FFQs summarizing fruit and vegetable intake, alcohol intake, meat intake, hypo-caloric die2013-01-01T00:00:00Z2013 Apr2026-06-06T18:20:07.108Z2026-06-05T03:07:42.776ZS-EPMC36088902354313610.1007/s11306-012-0469-6