biostudies-literature00440Olivares-Romero JLNIGMS NIH HHS3411-3https://www.ebi.ac.uk/biostudies/studies/S-EPMC3625140biostudies-literatureUnknown135(9)An efficient and versatile method for the enantioselective epoxidation of both tertiary allylic and homoallylic alcohols catalyzed by Hf(IV)-bishydroxamic acid (BHA) complexes is described. Asymmetric epoxidation, kinetic resolution, and desymmetrization have been developed, demonstrating the flexible nature of the Hf(IV)-BHA system. This is the first report in which these substrates were obtained with enantioselectivities of up to 99%.Journal of the American Chemical SocietyCatalytic enantioselective epoxidation of tertiary allylic and homoallylic alcohols.PMC3625140R01 GM0684332R01GM068433Li ZYamamoto HOlivares-Romero JL44falseCatalytic enantioselective epoxidation of tertiary allylic and homoallylic alcohols.An efficient and versatile method for the enantioselective epoxidation of both tertiary allylic and homoallylic alcohols catalyzed by Hf(IV)-bishydroxamic acid (BHA) complexes is described. Asymmetric epoxidation, kinetic resolution, and desymmetrization have been developed, demonstrating the flexible nature of the Hf(IV)-BHA system. This is the first report in which these substrates were obtained with enantioselectivities of up to 99%.2013-01-01T00:00:00Z2013 Mar2024-11-21T05:54:28.346Z2019-03-26T23:30:03ZS-EPMC36251402340608210.1021/ja401182a