biostudies-literatureAwasthi SMedical Research Council1478-86https://www.ebi.ac.uk/biostudies/studies/S-EPMC3647147biostudies-literatureUnknown381(9876)<h4>Background</h4>In north India many pre-school children are underweight, many have intestinal worms, and 2-3% die at ages 1·0-6·0 years. We used the state-wide Integrated Child Development Service (ICDS) infrastructure to help to assess any effects of regular deworming on mortality.<h4>Methods</h4>Participants in this cluster-randomised study were children in catchment areas of 8338 ICDS-staffed village child-care centres (under-5 population 1 million) in 72 administrative blocks. Groups of four neighbouring blocks were cluster-randomly allocated in Oxford between 6-monthly vitamin A (retinol capsule of 200,000 IU retinyl acetate in oil, to be cut and dripped into the child's mouth every 6 months), albendazole (400 mg tablet every 6 months), both, or neither (open control). Analyses of Lancet (London, England)Population deworming every 6 months with albendazole in 1 million pre-school children in North India: DEVTA, a cluster-randomised trial.PMC3647147MC_U137686857Narang NLal AHaq ILal BPrasad MKumar MKumar NUpreti DKAhmad HKumar RKumar SAhmad ASingh HSharma AShukla SSKazi MSingh SNeetu LPant PKParween STiwari AKNajeeb SChaturvedi ARai BSharma MJoshi VCRichards SMBajpai DMani SSRehman HSaxena NPande VChandra HRead SDas RSrivastava VKChandra ATandon ADwivedi APeto RPal CSrivastava APrakash NShukla VBChandra RDwivedi SChandra UVerma SSTripathi MPandey LShukla LBundy DShukla HBahadur JShukla KBShukla VKumar DChitransh DShukla RShukla SDEVTA (Deworming and Enhanced Vitamin A) teamKumar KAyyar LMaseeh AAwasthi SRastogi TKumar ARashid ZfalsePopulation deworming every 6 months with albendazole in 1 million pre-school children in North India: DEVTA, a cluster-randomised trial.<h4>Background</h4>In north India many pre-school children are underweight, many have intestinal worms, and 2-3% die at ages 1·0-6·0 years. We used the state-wide Integrated Child Development Service (ICDS) infrastructure to help to assess any effects of regular deworming on mortality.<h4>Methods</h4>Participants in this cluster-randomised study were children in catchment areas of 8338 ICDS-staffed village child-care centres (under-5 population 1 million) in 72 administrative blocks. Groups of four neighbouring blocks were cluster-randomly allocated in Oxford between 6-monthly vitamin A (retinol capsule of 200,000 IU retinyl acetate in oil, to be cut and dripped into the child's mouth every 6 months), albendazole (400 mg tablet every 6 months), both, or neither (open control). Analyses of 2013-01-01T00:00:00Z2013 Apr2025-04-03T22:11:15.507Z2019-03-27T01:09:39ZS-EPMC36471472349885010.1016/S0140-6736(12)62126-6