{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Dawson HD"],"funding":["NCRR NIH HHS","NIAID NIH HHS","Wellcome Trust","Biotechnology and Biological Sciences Research Council"],"pagination":["332"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC3658956"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["14"],"pubmed_abstract":["Background
The domestic pig is known as an excellent model for human immunology and the two species share many pathogens. Susceptibility to infectious disease is one of the major constraints on swine performance, yet the structure and function of genes comprising the pig immunome are not well-characterized. The completion of the pig genome provides the opportunity to annotate the pig immunome, and compare and contrast pig and human immune systems.Results
The Immune Response Annotation Group (IRAG) used computational curation and manual annotation of the swine genome assembly 10.2 (Sscrofa10.2) to refine the currently available automated annotation of 1,369 immunity-related genes through sequence-based comparison to genes in other species. Within these genes, we annotated 3,"],"journal":["BMC genomics"],"pubmed_title":["Structural and functional annotation of the porcine immunome."],"pmcid":["PMC3658956"],"funding_grant_id":["BBS/E/D/20231759","BB/I025328/1","BB/G004013/1","T32 AI083196","P20-RR017686","BBS/E/D/20251969","EC FP6","BBS/E/D/20211550","BB/E010520/2","BB/E010520/1","BBS/E/D/20211552","098051","T32 AI83196"],"pubmed_authors":["Bed'Hom B","Reecy JM","Zhang J","Hu Z","Astley M","Lunney JK","Mann KM","Cheng RP","Bystrom M","Steward C","Zhao SH","Sang Y","Kataria R","Kapetanovic R","Hunt T","Archibald AL","Chen C","Rogel-Gaillard C","Tuggle CK","Huang TH","Badaoui B","Giuffra E","Toki D","Loveland JE","Anselmo A","Wilming L","Freeman TC","Schwartz JC","Hardy M","Lloyd D","Pascal G","Blecha F","Ait-Ali T","Botti S","Fritz E","Thomas M","Dawson HD","Amid C","Murtaugh MP","Snow C","Morozumi T","Gilbert JG","Beraldi D","Hume DA","Harrow JL","Berman D","Carvalho-Silva D","Uenishi H","Shinkai H","Kay M"],"additional_accession":[]},"is_claimable":false,"name":"Structural and functional annotation of the porcine immunome.","description":"Background
The domestic pig is known as an excellent model for human immunology and the two species share many pathogens. Susceptibility to infectious disease is one of the major constraints on swine performance, yet the structure and function of genes comprising the pig immunome are not well-characterized. The completion of the pig genome provides the opportunity to annotate the pig immunome, and compare and contrast pig and human immune systems.Results
The Immune Response Annotation Group (IRAG) used computational curation and manual annotation of the swine genome assembly 10.2 (Sscrofa10.2) to refine the currently available automated annotation of 1,369 immunity-related genes through sequence-based comparison to genes in other species. Within these genes, we annotated 3,","dates":{"release":"2013-01-01T00:00:00Z","publication":"2013 May","modification":"2026-05-02T04:49:08.272Z","creation":"2026-04-07T17:36:46.563Z"},"accession":"S-EPMC3658956","cross_references":{"pubmed":["23676093"],"doi":["10.1186/1471-2164-14-332"]}}