biostudies-literaturePresset MNCRR NIH HHSNIGMS NIH HHS1528-31https://www.ebi.ac.uk/biostudies/studies/S-EPMC3663910biostudies-literatureUnknown15(7)Potassium vinyltrifluoroborate was found to be an efficient partner with benzamide derivatives for Rh(III)-catalyzed annulations. 4-Trifluoroboratotetrahydroisoquinolones were generated under mild conditions, affording a regioisomerically complementary substitution pattern to other alkenes in related reactions. These new boron-containing building blocks were derivatized by N-arylations, retaining the boron substituent for further elaboration.Organic lettersComplementary regioselectivity in Rh(III)-catalyzed insertions of potassium vinyltrifluoroborate via C-H activation: preparation and use of 4-trifluoroboratotetrahydroisoquinolones.PMC3663910R01 GM035249S10 RR016640Presset MMolander GAOehlrich DRombouts FfalseComplementary regioselectivity in Rh(III)-catalyzed insertions of potassium vinyltrifluoroborate via C-H activation: preparation and use of 4-trifluoroboratotetrahydroisoquinolones.Potassium vinyltrifluoroborate was found to be an efficient partner with benzamide derivatives for Rh(III)-catalyzed annulations. 4-Trifluoroboratotetrahydroisoquinolones were generated under mild conditions, affording a regioisomerically complementary substitution pattern to other alkenes in related reactions. These new boron-containing building blocks were derivatized by N-arylations, retaining the boron substituent for further elaboration.2013-01-01T00:00:00Z2013 Apr2025-04-04T23:39:55.098Z2019-03-27T01:10:24ZS-EPMC36639102349603310.1021/ol400307d