{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["69(Pt 6)"],"submitter":["Maiga A"],"pubmed_abstract":["ρ-Da1a toxin from eastern green mamba (Dendroaspis angusticeps) venom is a polypeptide of 65 amino acids with a strong affinity for the G-protein-coupled α(1A)-adrenoceptor. This neurotoxin has been crystallized from resolubilized lyophilized powder, but the best crystals grew spontaneously during lyophilization. The crystals belonged to the trigonal space group P3(1)21, with unit-cell parameters a = b = 37.37, c = 66.05 Å, and diffracted to 1.95 Å resolution. The structure solved by molecular replacement showed strong similarities to green mamba muscarinic toxins."],"journal":["Acta crystallographica. Section F, Structural biology and crystallization communications"],"pagination":["704-9"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC3668600"],"repository":["biostudies-literature"],"pubmed_title":["Crystallization of recombinant green mamba ρ-Da1a toxin during a lyophilization procedure and its structure determination."],"pmcid":["PMC3668600"],"pubmed_authors":["Gilles N","Servent D","Stura EA","Lorphelin A","Bellanger L","Maiga A","Mourier G","Vera L","Marchetti C"],"additional_accession":[]},"is_claimable":false,"name":"Crystallization of recombinant green mamba ρ-Da1a toxin during a lyophilization procedure and its structure determination.","description":"ρ-Da1a toxin from eastern green mamba (Dendroaspis angusticeps) venom is a polypeptide of 65 amino acids with a strong affinity for the G-protein-coupled α(1A)-adrenoceptor. This neurotoxin has been crystallized from resolubilized lyophilized powder, but the best crystals grew spontaneously during lyophilization. The crystals belonged to the trigonal space group P3(1)21, with unit-cell parameters a = b = 37.37, c = 66.05 Å, and diffracted to 1.95 Å resolution. The structure solved by molecular replacement showed strong similarities to green mamba muscarinic toxins.","dates":{"release":"2013-01-01T00:00:00Z","publication":"2013 Jun","modification":"2025-04-19T14:57:12.694Z","creation":"2019-03-27T01:10:39Z"},"accession":"S-EPMC3668600","cross_references":{"pubmed":["23722859"],"doi":["10.1107/S1744309113011470","10.1107/s1744309113011470"]}}