{"database":"biostudies-literature","file_versions":[],"scores":{"citationCount":0,"reanalysisCount":0,"viewCount":45,"searchCount":0},"additional":{"submitter":["Meyer MJ"],"funding":["NCI NIH HHS","NIGMS NIH HHS"],"pagination":["1577-9"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC3673217"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["29(12)"],"pubmed_abstract":["INstruct is a database of high-quality, 3D, structurally resolved protein interactome networks in human and six model organisms. INstruct combines the scale of available high-quality binary protein interaction data with the specificity of atomic-resolution structural information derived from co-crystal evidence using a tested interaction interface inference method. Its web interface is designed to allow for flexible search based on standard and organism-specific protein and gene-naming conventions, visualization of protein architecture highlighting interaction interfaces and viewing and downloading custom 3D structurally resolved interactome datasets.INstruct is freely available on the web at http://instruct.yulab.org with all major browsers supported."],"journal":["Bioinformatics (Oxford, England)"],"pubmed_title":["INstruct: a database of high-quality 3D structurally resolved protein interactome networks."],"pmcid":["PMC3673217"],"funding_grant_id":["R01 GM104424","R01 GM097358","1T32GM083937","R01 CA167824","T32 GM083937"],"pubmed_authors":["Meyer MJ","Wang X","Das J","Yu H"],"view_count":["45"],"additional_accession":[]},"is_claimable":false,"name":"INstruct: a database of high-quality 3D structurally resolved protein interactome networks.","description":"INstruct is a database of high-quality, 3D, structurally resolved protein interactome networks in human and six model organisms. INstruct combines the scale of available high-quality binary protein interaction data with the specificity of atomic-resolution structural information derived from co-crystal evidence using a tested interaction interface inference method. Its web interface is designed to allow for flexible search based on standard and organism-specific protein and gene-naming conventions, visualization of protein architecture highlighting interaction interfaces and viewing and downloading custom 3D structurally resolved interactome datasets.INstruct is freely available on the web at http://instruct.yulab.org with all major browsers supported.","dates":{"release":"2013-01-01T00:00:00Z","publication":"2013 Jun","modification":"2021-02-19T19:03:54Z","creation":"2019-03-27T01:10:52Z"},"accession":"S-EPMC3673217","cross_references":{"pubmed":["23599502"],"doi":["10.1093/bioinformatics/btt181"]}}